No Prognostic or Molecular Disparity Between Synchronous and Metachronous Metastases in Differentiated Thyroid Cancer: Insight From Middle Eastern Cohort

The goal of this observational study is to compare the clinical outcomes, molecular features, and immune profiles of patients with synchronous and metachronous distant metastases in Saudi cohort with well characterized differentiated thyroid cancer. The main question it aims to answer is whether timing of metastasis is associated with distinct prognostic or biological behavior in differentiated thyroid cancer from a large Middle Eastern cohort

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Key information

Conditions

Differentiated Thyroid Cancer

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Synchronous or metachronous distant metastases

Exclusion criteria

Not DTC
No distant metastases

Treatment and study plan

No additional drugs(control Group)

Other

No intervention

Primary outcomes

Overall survival

Time frame: 5 years

Secondary outcomes

Thyroid cancer-specific survival

Time frame: 5 years

Sponsors and collaborators

Lead sponsor

King Faisal Specialist Hospital & Research Center

Other

Registry information

Important dates

Study start: 1988
Primary completion: 2018
Study completion: 2024
First posted: Aug 11, 2025
Registry last updated: Aug 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed