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OpenTrials
Completed

NCT Number: NCT02436629

Nitrate for High Intensity Intermittent Exercise

The objective of the current study is to assess the effect of 6-day dietary nitrate ingestion on high intensity intermittent sports performance in recreational soccer players.

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Key information

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 4

Primary location

Maastricht University Medical Centre+

Maastricht, Limburg, 6200MD, Netherlands

About this study

Oral ingestion of nitrate (NO3-) in the form of both nitrate salts and concentrated red beetroot juice has been shown to significantly lower blood pressure at rest and to improve exercise performance during cycle time trials. Furthermore, a positive exercise performance effect of nitrate ingestion has been observed in recreational athletes during intermittent exercise. However, this was achieved after acute supplementation with a substantial dose of dietary nitrate. Whether similar ergogenic effects of nitrate supplementation can be achieved with a more conventional 6-day nitrate supplementation protocol with a lower daily dose remains to be established. Based on the gaps in current literature, our main goal will be to gain further insight into the effects of a 6-day nitrate supplementation protocol on high intensity intermittent exercise performance in recreational athletes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy P
  • Players of the first two senior selection teams of a regional soccer club competing at the 3rd KNVB level or higher
  • Training ≥2 days a week
  • 18-40 years
  • Male

Exclusion criteria

  • Use of medication
  • Injury prohibiting them from performing the exercise protocol effectively
  • Smoking
  • Currently supplementing diet with nitrate
  • Lactose intolerance

Treatment and study plan

Nitrate-rich concentrated beetroot juice

Dietary Supplement

James White, Beet It Sport Shot, 70ml (Standard)

Nitrate-depleted concentrated red beetroot juice

Dietary Supplement

Beet It Sport Shot, 70ml (Placebo)

Primary outcomes

  1. Total distance covered during the Yo-Yo Intermittent Recovery 1 test (Yo-Yo IR1 test)

    Time frame: Performance 3 hours post red beetroot juice ingestion

Secondary outcomes

  1. Plasma concentration of nitrite and nitrate

    Time frame: Concetrations 3 hours post red beetroot juice ingestion

  2. Salivary concentration of nitrite and nitrate

    Time frame: Concetrations 3 hours post red beetroot juice ingestion

Other outcomes

  1. Baseline characteristics

    Time frame: 30 min during visit 1 (Screening)

    Height, body weight, age, BMI

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

The Effect of Nitrate Supplementation on Sport Performance: High Intensity Intermittent Performance in Recreational Athletes

Acronym: NITR-ITE

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
May 7, 2015
Registry last updated
Jul 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.