University of Applied Sciences
Jena, Thuringia, 07745, Germany
Completed
NCT Number: NCT03358550
Night Myopia and Dark Focus of Accommodation
Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D. In addition to the measurement of dark focus, the aim of this study was to investigate the influence of an imaginary target at finite distances on the state of accommodation at scotopic luminance.
Completed
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Notify MeKey information
Conditions
Age range
22 year–39 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
About this study
Accommodation was measured by using an open-field autorefractor (WAM 5500, GRAND SEIKO). Full corrected right eyes of 39 subjects aged from 18 to 40 years were investigated in this randomized, cross-sectional study. Accommodation measurements in photopic luminance were taken for 6 m of empty field and for optotype fixation at 2 m, 1 m and 0.5 m. At scotopic luminance, dark focus of accommodation was examined directly after darkening and after 10 min of dark adaptation. After adaptation, subjects had to visualize imaginary targets in the four distances while accommodation was measured.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- age 18 - 44
- visual acuity at least 0.8 (5/6)
Exclusion criteria
- medication with an impact on the visual system
- visual disease or disease with an impact on the visual system
- pregnancy or other hormonal variances
- drug usage
- overfatigue at the period of investigation
- mental handicap
Treatment and study plan
Accommodation Measurement
Diagnostic TestAccommodation was measured for different distances and light conditions.
Primary outcomes
-
Shift of accommodation in scotopic luminance (Dark focus)
Time frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for empty field (dark focus of accommodation)
Secondary outcomes
-
Difference of accommodation for 2 m target
Time frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 2 m
-
Difference of accommodation for 1 m target
Time frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 1 m
-
Difference of accommodation for 0.5 m target
Time frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 0.5 m
Sponsors and collaborators
Lead sponsor
University of Applied Sciences Jena
Other
Registry information
Official study title
Influence of an Imaginary Target on the State of Accommodation Under Scotopic Conditions
Important dates
- Study start
- 2017
- Primary completion
- 2017
- Study completion
- 2017
- First posted
- Nov 30, 2017
- Registry last updated
- Nov 30, 2017
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.