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Active, Not Recruiting

NCT Number: NCT07164404

Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients

Investigators are evaluating an EHR-based, non-interruptive alert to increase NRT prescribing in the hospital and at discharge for hospitalized patients. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Medical University of South Carolina

Charleston, South Carolina, 29407, United States

About this study

Efforts to decrease cancer-related morbidity and mortality include increasing smoking cessation, however smoking remains prevalent. Classically, alerts within the electronic health record (EHR) are implemented to address gaps in care, yet studies suggest typical EHR alerts are often overridden and ignored. In this study, the investigators aim to decrease the incidence and burden of disease by including hospitalists as part of the multidisciplinary care team by implementing and evaluating a novel non-interruptive EHR alert embedded within a provider note as a tool to increase prescription of nicotine replacement therapy to patients who smoke upon admission to and discharge from the hospital. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Patients

Inclusion criteria

  • Hospitalized patients admitted to a General Medicine Service at MUSC Charleston
  • Identified as actively smoking tobacco via nursing admission screening
  • Admitted by a resident physician participating in the study (as indicated by the H&P note)

Exclusion criteria

  • None

Resident Physicians:

Inclusion criteria

  • Internal medicine resident physicians rotating on the hospitalist service at MUSC Health Charleston

Exclusion criteria

  • None

Treatment and study plan

EHR alert

Other

EHR embedded alert into the admission note template, where it automatically inserts smoking history, prompts NRT prescribing in the hospital, and offers referral to outpatient follow up.

Primary outcomes

  1. Nicotine Replacement Therapy (NRT) prescribing rates during hospitalization

    Time frame: During hospitalization, assessed from admission to discharge (average of 3-7 days)

  2. Nicotine Replacement Therapy (NRT) prescribing rates at discharge

    Time frame: During hospitalization, assessed from admission to discharge (average of 3-7 days)

  3. Rate of referral to outpatient tobacco cessation clinic

    Time frame: During hospitalization, assessed from admission to discharge (average of 3-7 days)

Sponsors and collaborators

Lead sponsor

Medical University of South Carolina

Other

Collaborators

  • South Carolina Clinical & Translational Research Institute (SCTR)

Registry information

Official study title

Increasing Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients Using an Innovative Non-Interruptive Alert Within the Electronic Health Record Provider Note

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 10, 2025
Registry last updated
May 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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