New Technique for Uretero-ileal Anastomosis for Patient With Bladder Cancer Who Are Suitable for Orthotopic Neobladder

This was a prospective study conducted from 2014 to 2017 in Ain shams university, 73 patients were enrolled from outpatient clinic diagnosed with muscle invasive bladder cancer and candidate for radical cystectomy and orthotopic urinary diversion, 45 patients were included according to patient's acceptance and the inclusion and exclusion criteria.

After having a written informed consent, all selected patients were assessed by detailed history and physical examination, contrast enhanced pelvi-abdominal Computed tomography (CT) scan (for patients with serum creatinine <1.5 mg/dl). Laboratory investigations in the form of complete blood count, coagulation profile, electrolytes, renal and liver function tests. Bowel preparation was done to all patients one or two days before operation.

Cases were diverted using a U-shaped pouch with uretero-ileal anastomosis done in a single trough combining the extramural serous-lined tunnel and Wallace techniques.

The inclusion criteria:

• Patients with invasive bladder cancer (T2, T3).
• good performance status
• patients with serum creatinine ≤ 2 mg/dL
• prostatic urethra free of tumor.
• willing to adhere to the follow up regimen.

The exclusion criteria:

• patients not fit for surgical intervention.
• patients with renal or hepatic dysfunction.
• male patients with positive urethral biopsy or diffuse CIS.
• female patients with bladder neck or vaginal involvement.
• concomitant pathological condition in the distal ureters necessitating the excision of a significant segment that hinders proper fashioning of uretero-ileal anastomosis.
• Cases with markedly dilated ureters.