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Completed

NCT Number: NCT01016496

New Perspectives in the Rehabilitation of Children With Motor Disorders : the Role of the Mirror Neuron System

Evidence exists that the activation of actions activates the same cortical motor areas that are involved in the performance of the observed actions. The neural substrate for this phenomena is the mirror neuron system. It is generally assumed that mirror neurons have a basic role in understanding the intentions of others and in imitation learning. There is evidence that action observation has a positive effect on rehabilitation of motor disorders after stroke. The aim of this study is to demonstrate that action observation followed by the repetition of the actions previously observed has a positive impact on rehabilitation of the upper limb in children affected by hemiplegia as a consequence of Cerebral Palsy. In particular, the purpose is to assess if mirror neurons could improve the amount, the quality and the velocity of movements and the cooperation between the two upper extremities.

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Key information

Age range

6 year–12 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hospital of Parma, Parma, Italy

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • children with hemiplegia and
  • Melbourne assessment > 50 points

Exclusion criteria

  • inability to collaborate
  • pharmacoresistant epilepsy
  • inability to imitate gestures
  • sensitivity disorders

Treatment and study plan

Action observation therapy

Other

15 consecutive sessions of 18 minutes, plus repetition

repetition of gestures

Other

15 consecutive session of visual games, plus repetition of gestures

Primary outcomes

  1. Melbourne Assessment of unilateral limb function

    Time frame: T0=baseline, Tend (week three) , T2(two months) T6months (six months after the completion of the training)

Secondary outcomes

  1. Assisting Hand Assessment

    Time frame: T0, Tend, T2, T6

  2. Jebsen-Taylor

    Time frame: T0, Tend, T2, T6

  3. Abilhand emikids

    Time frame: T0, Tend, T2, T6

Sponsors and collaborators

Lead sponsor

Stefania Costi

Other

Collaborators

  • IRCCS Fondazione Stella Maris
  • University of Parma

Registry information

Official study title

Rehabilitation Strategies in Children With Neuro-motor Disorders Due to the Impairment of the Central Nervous System or the Peripheral Nervous System

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Nov 19, 2009
Registry last updated
Jun 24, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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