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NCT Number: NCT07676630

Neuroscience-Based Exercise Training in Female Volleyball Players

24 volunteer professional female volleyball players (aged 16-21), licensed in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 and 3, will be included in the study. Participants will be randomized into intervention (n=12) and control (n=12) groups using www.randomizer.org. The intervention group will receive an 8-week (3 days/week) neuro-athletic exercise training program, including eye warm-up exercises and volleyball-specific visual and motor coordination stations, in addition to their regular training. The control group will continue with regular training only. Both groups will have equal total training time.

Visual attention and decision-making strategies will be measured with a wearable eye-tracking system (Pupil Labs Invisible) during a serve task. Cortical activation (oxygenated and deoxygenated hemoglobin levels) in the frontal cortex during the same serve task will be measured simultaneously with functional near-infrared spectroscopy (fNIRS). Sport-specific physical fitness will be evaluated with the T-Agility Test, radar gun serve speed measurement, VERT wearable jump analysis system, Y-Balance Test, and sit-and-reach test.

All assessments will be conducted before training begins and after the 8-week program. The study aims to determine whether neuro-athletic exercise training improves cortical activation, visual attention, decision-making processes, and sport-specific physical fitness parameters in professional female volleyball players, compared to a control group receiving regular training only.

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Key information

Age range

16 year–21 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Istinye University Physiotherapy and Rehabilitation Practice and Research Center

Istanbul, Zeytinburnu, 34010, Turkey (Türkiye)

Location status: Recruiting

Location contact

OZGE ECEM SENEL, PT, MSc

CONTACT

[email protected]

+905392642868

About this study

Volleyball requires high-level cognitive and physical performance, including agility, decision-making, and motor coordination, often performed under time pressure. Neuro-athletic training is an emerging approach that integrates neurofeedback techniques with sport-specific exercises, targeting cognitive and motor functions through neuroplasticity-based principles. This approach aims to improve afferent and efferent neural system coordination, sensory processing, and motor control, which may translate into improved athletic performance and reduced injury risk.

This study investigates the effect of an 8-week neuro-athletic exercise training program on cortical activation, visual attention, decision-making processes, and sport-specific physical fitness in professional female volleyball players, using a randomized, controlled, parallel-group design.

A total of 24 female volleyball players, licensed in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 and League 3, aged 16-21 years, will be randomly allocated into an intervention group (n=12) and a control group (n=12) using www.randomizer.org. Sample size was determined using G*Power software (independent samples t-test, between-group comparison) with 95% power, 0.05 type-1 error, and a high effect size (f=0.75), with a 20% margin added to account for potential dropout.

The intervention group will receive a structured neuro-athletic exercise training program, 3 days per week for 8 weeks, added to their regular volleyball training as a warm-up component. The program includes eye warm-up exercises (eye massage, palming) and volleyball-specific visual-motor coordination stations: Saccade and Anti-Saccade stations, Smart Optometry station, Brock String, Star Chart station, and Pinhole Glasses Small Area Game. The control group will continue their regular training, warm-up, and cool-down routine without additional intervention. Total training time will be kept equal between groups to prevent differences in overall training load.

All participants will be assessed before the intervention begins and after the 8-week program. Primary assessments include:

Eye-tracking (Pupil Labs Invisible wearable system) to evaluate visual attention, gaze fixation, and visual search strategies during a serve task.

Functional near-infrared spectroscopy (fNIRS) to measure frontal cortex oxygenated (HbO) and deoxygenated (HbR) hemoglobin levels simultaneously during the same serve task, comparing pre-task, during-task, and post-task signal changes.

Secondary assessments include sport-specific physical fitness parameters:

T-Agility Test (agility, change of direction, coordination), with reaction time recorded via BlazePod integrated lights.

Serve speed, measured using a radar gun (Bushnell Velocity Speed Gun). Vertical jump performance (jump height, peak velocity, landing force), measured using the VERT wearable jump analysis system.

Y-Balance Test (dynamic balance and proprioception). Sit-and-Reach Test (lumbar and hamstring flexibility).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Licensed female volleyball player in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 or League 3
  • Aged between 16 and 21 years
  • Actively participating in the sport for at least 3 years

Exclusion criteria

  • Any history of musculoskeletal surgery
  • An injury within the last 3 months that prevented participation in training or competition
  • Any diagnosed visual impairment, visual function disorder, or vestibular system-related problem

Treatment and study plan

Exercise

Behavioral

An 8-week (3 days/week) structured program added to regular training, combining: (1) eye warm-up exercises (eye massage, palming) and (2) volleyball-specific visual-motor coordination stations, including Saccade, Anti-Saccade, and Smart Optometry stations (targeting visual tracking, reaction speed, and eye-hand coordination), Brock String (depth perception and eye-hand coordination), Star Chart station (visual scanning and spatial awareness), and Pinhole Glasses Small Area Game (restricted peripheral vision to enhance focused attention and quick decision-making). Sessions are conducted by a physiotherapist, with total training time matched to the control group.

Primary outcomes

  1. Functional near-infrared spectroscopy

    Time frame: Baseline and after 8 weeks

    Cortical Activation During Serve Task (fNIRS), measured using functional near-infrared spectroscopy (fNIRS) during a serve task, comparing pre-task, during-task, and post-task signal changes. Change in oxygenated (HbO) and deoxygenated (HbR) hemoglobin levels in the frontal cortex.

  2. Pupil Lab Invisible Eye Tracker

    Time frame: Baseline and after 8 weeks

    Visual Attention and Decision-Making (Eye-Tracking Parameters). Measured using a wearable eye-tracking system (Pupil Labs Invisible) during a serve task, including total fixation duration and visual scan path parameters, automatically quantified using Pupil Player software. Measured change in gaze fixation duration and visual search patterns

Secondary outcomes

  1. T-Agility Test

    Time frame: Baseline and after 8 weeks

    Time to complete the T-Agility Test course, measured in seconds with a stopwatch; reaction time also recorded via BlazePod integrated lights in milliseconds. Measured change in T-Agility Test completion time

  2. Serve Speed

    Time frame: Baseline and after 8 weeks

    Measured change in serve speed. Measured in km/h using a radar gun (Bushnell Velocity Speed Gun) during 5 successful serves; highest recorded value used for analysis.

  3. Vertical Jump Performance

    Time frame: Baseline and after 8 weeks

    Measured using the VERT wearable jump analysis system across 5 maximal vertical jumps using the countermovement jump technique. Measured change in jump height, peak jump velocity, and landing force

  4. Y-Balance Test

    Time frame: Baseline and after 8 weeks

    Measured change in Y-Balance Test composite score. Composite reach score calculated from anterior, posteromedial, and posterolateral reach directions, normalized to limb length.

  5. Sit-and-Reach Test

    Time frame: Baseline and after 8 weeks

    Measured change in sit-and-reach distance. Measures lumbar and hamstring muscle flexibility using a sit-and-reach box; distance recorded in centimeters.

Study contacts

Contact information is provided by the study sponsor or research team.

OZGE ECEM SENEL, PT, MSc

CONTACT

[email protected]

+905392642868

Sponsors and collaborators

Lead sponsor

Özge Ecem Şenel

Other

Registry information

Official study title

Effect of Neuroscience-Based Exercise Training on Cortical Activation, Focus, and Performance in Professional Female Volleyball Players

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 30, 2026
Registry last updated
Jun 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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