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Completed

NCT Number: NCT01781364

Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia

Completed

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Key information

Conditions

Psychosis Mental Disorders Psychotic Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

17 year–37 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University Konstanz

Konstanz, Baden-Wurttemberg, 78464, Germany

About this study

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Early Onset Psychosis

Exclusion criteria

  • Chronicity
  • Insufficient German skills

Treatment and study plan

Brain Fitness Training, Posit Science SF

Behavioral

Computer aided cognitive training based on principles of neuroplasticity

Primary outcomes

  1. change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activity

    Time frame: baseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up

Secondary outcomes

  1. change from baseline in GAF score at 3-months and 7-moths follow-up

    Time frame: baseline, 3-months follow-up, 7-months follow-up

Sponsors and collaborators

Lead sponsor

University of Konstanz

Other

Registry information

Important dates

Study start
2012
Primary completion
2014
Study completion
2014
First posted
Feb 1, 2013
Registry last updated
Dec 16, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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