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NCT Number: NCT07293416

Neuropilates and Otago Exercises on Balance, Posture and Functional Independence in Chronic Stroke

This randomized clinical trial will be conducted at various physical therapy clinics of Faisalabad over a six-month period, enrolling a total of 32 participants selected through non probability convenience sampling technique. Participants will be randomly assigned to one of two groups: those undergoing Neuropilates and those performing Otago exercises, with each group consisting of 16 individuals. Assessments will utilize the TUG (Timed Up and Go) to evaluate balance, the Postural Assessment Scale for Stroke Patients (PASS) for posture, and the Functional Independence Measure (FIM) for functional independence. Pre-intervention assessments will establish baseline measures, followed by evaluations at 4 weeks, and post-intervention to track progress. Data analysis will be conducted using SPSS 26 software, allowing for a comprehensive comparison of the interventions' effectiveness. The findings from this study will contribute valuable insights for clinicians and rehabilitation specialists, enhancing therapeutic strategies to support chronic stroke patients in regaining their independence.

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Key information

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Al-Mahmood Physiotherapy Clinic, Faisalabad, Pakistan

Loading trial locations.

About this study

Chronic stroke survivors often face profound challenges that considerably impact their balance, posture, and functional independence. These issues can compromise their ability to perform daily activities, reduce their quality of life, and lead to increased dependency on caregivers. Effective rehabilitation strategies are essential for improving these aspects of recovery. Neuropilates, a novel approach that merges the foundational principles of Pilates with targeted neurological rehabilitation techniques, has shown promise in enhancing physical and cognitive function. By focusing on core strength, flexibility, and body awareness, Neuropilates aims to facilitate motor learning and improve overall stability. This study is designed to compare the effectiveness of Neuropilates with Otago exercises-an evidence-based program specifically designed to enhance strength and balance in older adults-on key rehabilitation outcomes for individuals living with chronic stroke. The Otago program emphasizes lower limb strength and balance training, making it a relevant comparison for assessing improvements in functionality.

The randomized clinical trial will be conducted at various physical therapy clinics of Faisalabad over a six-month period, enrolling a total of 32 participants selected through non probability convenience sampling technique. Participants will be randomly assigned to one of two groups: those undergoing Neuropilates and those performing Otago exercises, with each group consisting of 16 individuals. Assessments will utilize the TUG (Timed Up and Go) to evaluate balance, the Postural Assessment Scale for Stroke Patients (PASS) for posture, and the Functional Independence Measure (FIM) for functional independence. Pre-intervention assessments will establish baseline measures, followed by evaluations at 4 weeks, and post-intervention to track progress. Data analysis will be conducted using SPSS 26 software, allowing for a comprehensive comparison of the interventions' effectiveness. The findings from this study will contribute valuable insights for clinicians and rehabilitation specialists, enhancing therapeutic strategies to support chronic stroke patients in regaining their independence.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 40-70 years
  • Both male and female
  • Chronic stroke, 6-18 months post-stroke
  • Stroke severity score >6 on NIHSS
  • MMSE ≥24

Exclusion criteria

  • • Symptoms of global or receptive aphasia
  • Other neurological disorders: tumors, anoxia, TBI, neurodegenerative diseases, ataxia.
  • Significant cardiorespiratory conditions
  • Currently receiving other complementary interventions
  • Severe motor impairment preventing safe participation

Treatment and study plan

neuropilates

Other

50 minutes session of Neuropilates thrice a week for total of eight weeks which will include activation warm-up exercises for 10 minutes, main exercises for 30 minutes and cool-down exercises for 10 minutes

otago exercises

Other

50 minutes each session of Otago exercise thrice a week for total of eight weeks which will include, muscle strengthening, balance training and 2x week 30 minutes walking session. Depending on the individual's strength and mobility, the exercises will be progressed, by increasing the amount of repetitions or weight

Primary outcomes

  1. The Postural Assessment Scale for Stroke (PASS)

    Time frame: baseline, 4thweek, 8thweek

    The Postural Assessment Scale for Stroke (PASS) is designed to evaluate postural control after stroke. It consists of 12 four-level items assessing the ability to maintain or change positions in lying, sitting, and standing. Scores range from 0 to 36, with 0-12 indicating poor, 13-24 moderate, and 25-36 good postural control. The PASS has excellent inter-rater reliability (α = 0.88, range 0.64-1) and total score reliability (r = 0.99, p < 0.001). Test-retest reliability in chronic stroke patients is also high (ICC = 0.84-0.97).

  2. The Functional Independence Measure (FIM)

    Time frame: baseline, 4thweek, 8thweek

    The Functional Independence Measure (FIM) is used to assess the functional independence of individuals recovering from illness or disability. It includes 18 items covering self-care, mobility, locomotion, communication, and social cognition. Each item is rated on a 7-point scale (1 = total dependence to 7 = complete independence), giving a total score between 18 and 126. Higher scores indicate greater independence. The FIM demonstrates high inter-rater reliability (ICC = 0.86-0.88).

  3. Timed Up and Go (TUG)

    Time frame: baseline, 4thweek , 8thweek

    The Timed Up and Go (TUG) test is a simple, quick, and reliable tool used to assess mobility, balance, and fall risk in individuals with neurological or musculoskeletal conditions. It measures the time taken to stand up from a chair, walk three meters, turn, return, and sit down. A cut-off time of 12 seconds or more indicates a high risk of falling. The test is suitable for people with stroke, Parkinson's disease, multiple sclerosis, hip fracture, or joint replacement. It requires only a chair, stopwatch, and three-meter mark and allows observation of gait, stability, and use of aids. The test shows a sensitivity and specificity of about 87% for identifying fall risk in the elderly population.

Study contacts

Contact information is provided by the study sponsor or research team.

Zobia Tariq, MS-NMPT

CONTACT

[email protected]

03321751888

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Comparative Effects of Neuropilates and Otago Exercises on Balance, Posture and Functional Independence in Individuals With Chronic Stroke

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 19, 2025
Registry last updated
Dec 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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