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Completed

NCT Number: NCT01770548

Neurophysiological Molecular and Developmental Analysis of the Glutamate Synapse in Autism

Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism

Completed

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Key information

Conditions

Autism Autism Spectrum Disorder Autistic Disorder Child Development Disorders, Pervasive Mental Disorders Neurodevelopmental Disorders

Age range

2 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHRU - Centre de Ressources Autisme (CRA), Brest, France

Loading trial locations.

About this study

Analysis about 50 genes in glutamate synapse

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • have a Pervasive Developmental Disorder

Exclusion criteria

  • N/A

Treatment and study plan

analysis of the glutamate synapse in autism

Genetic

Neurophysiological, molecular and developmental analysis of the glutamate synapse in autism

DNA collection

Genetic

DNA collection

Auditory evoked potentials

Other

auditory evoked potentials

Primary outcomes

  1. screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients

    Time frame: two years

Sponsors and collaborators

Lead sponsor

University Hospital, Tours

Other

Registry information

Official study title

Autism and Glutamatergic Synapse : Research of Genetic Mutations and Identification of Clinical and Neurophysiological Markers.

Acronym: NMDA-Autism

Important dates

Study start
2009
Primary completion
2011
Study completion
2014
First posted
Jan 17, 2013
Registry last updated
Jan 16, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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