Neurophysiological Characterization of Postherniotomy Pain

Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome. By performing quantitative sensory testing, the specific changes in pain patients will be revealed, thereby aiding in designing future treatment trials. MRI scans of the groin regions in pain patients and control patients will be evaluated by senior MRI specialists assessing potential pathology to the region (Mesh, inflammation, edema, funicle etc.) Assessors will be blinded to clinical status, and surgery.

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Key information

Conditions

Postoperative Pain Bronchial Diseases Bronchiolitis Bronchiolitis Obliterans Bronchiolitis Obliterans Syndrome Bronchitis Graft vs Host Disease Hernia Hernia, Abdominal Hernia, Inguinal Immune System Diseases Lung Diseases Lung Diseases, Obstructive Nervous System Diseases Neuralgia Neurologic Manifestations Neuromuscular Diseases Neuropathic Pain Organizing Pneumonia Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Peripheral Nervous System Diseases Postherniotomy Pain Postoperative Complications Respiratory Tract Diseases Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Danish Pain Research Centre, Aarhus, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male patients >18 yrs
Inguinal herniotomy >1 yr previously
No sign of hernia recurrence
Unilateral chronic groin pain lasting more than 3 months
Moderate/severe pain related impairment of everyday activities.

Exclusion criteria

Other causes of persistent pain in groin region (hip, other surgical procedures)

Treatment and study plan

Primary outcomes

Sensory function

Time frame: actual

Sponsors and collaborators

Lead sponsor

Rigshospitalet, Denmark

Other

Registry information

Official study title

Quantitative Sensory Testing in Persistent Postherniotomy Pain Patients

Important dates

Study start: 2006
Primary completion: 2012
Study completion: 2012
First posted: Jul 21, 2008
Registry last updated: Apr 7, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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