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NCT Number: NCT07372157

Neuromuscular Balance Exercise Effects in Overweight and Obese Individuals

This randomized controlled study aims to evaluate the effects of adding neuromuscular balance exercises to exercise programs on functional capacity, balance, and physical fitness in individuals with obesity. Forty participants will be randomly assigned to either a control group receiving aerobic and strength training exercises or an intervention group receiving aerobic and strength training combined with neuromuscular balance exercises. Both exercise programs will be conducted three times per week for eight weeks. Functional capacity, balance, and physical fitness outcomes will be assessed at baseline and after the intervention period. The findings are expected to contribute to the integration of balance-focused exercises into rehabilitation programs for individuals with obesity.

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Key information

Conditions

Overweight and Obesity Behavior Body Weight Motor Activity Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Fatih Sultan Mehmet Training and Research Hospital, Diabetes and Obesity Treatment Center

Istanbul, 34672, Turkey (Türkiye)

Location status: Recruiting

Location contact

Özden Ezgi E Üner, MD

CONTACT

+905323072789

About this study

This project will begin with initial assessments of volunteers to examine the effects of balance exercises on postural control and neuromuscular connections in obesity treatment. A multimodal exercise program (neuromuscular balance exercises, aerobic training, and resistance training) will be designed for individuals with obesity, and its effects on physical function, balance impairment, and weight management will be evaluated. In the first phase, participants' static and dynamic balance will be analyzed using clinical scales. In the second phase, an 8-week multimodal exercise program will be implemented, and the outcomes will be comparatively examined in relation to the weight loss process.

The study aims to provide scientific data to support the individualization of exercise programs by examining postural balance adaptations in response to changes in body composition during weight loss. The findings are expected to contribute to more comprehensive physical activity approaches in obesity management and to guide clinical applications.

This study adds a different perspective by evaluating the functional benefits of neuromuscular-based balance exercises in addition to traditional aerobic and strength training exercises. The assessment, conducted in individuals with obesity who have experienced weight loss, is expected to provide important findings for the interpretation and discussion of outcomes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteering to participate in the study
  • Having a BMI of 25-35 kg/m2
  • Not having undergone any surgical operation in the last 6 months

Exclusion criteria

  • Any musculoskeletal disorder or systemic disease that would prevent exercise
  • Balance problems due to any disease that could prevent exercise
  • Psychiatric or neurological disease affecting cooperation and cognitive functions
  • Acute pain for any reason
  • Chest pain
  • History of myocardial infarction within the last year
  • Congestive heart failure
  • Patient's inability to adhere to treatment

Treatment and study plan

Aerobic and strength training

Behavioral

The aerobic and strength training program consists of supervised exercise sessions performed three days per week for eight weeks. Aerobic exercises are conducted at a moderate intensity, and strength training targets major muscle groups using body weight and resistance-based exercises. Each session is structured to include warm-up, main exercise components, and cool-down phases.

Neuromuscular balance exercises

Behavioral

Neuromuscular balance exercises are added to the standard exercise program and are designed to improve postural control and balance. The exercises include progressive static and dynamic balance tasks and are performed three times per week for eight weeks under supervision.

Primary outcomes

  1. Dynamic Balance Performance (Four Step Square Test)

    Time frame: Baseline, at the 4th weeks and at the end of 8 weeks

    Dynamic balance will be assessed using the Four Step Square Test, which measures the time (in seconds) required to complete a multidirectional stepping sequence.

  2. Postural Control (Functional Reach Test)

    Time frame: Baseline, Week 4, and Week 8

    Postural control will be evaluated using the Functional Reach Test, which measures the maximal forward reach distance (in centimeters) while maintaining a fixed base of support.

  3. Walking Endurance (2-Minute Walk Test)

    Time frame: Baseline, at the 4th weeks and at the end of 8 weeks

    Walking endurance will be assessed using the 2-Minute Walk Test, which measures the total distance walked in meters over a two-minute period.

  4. Lower Extremity Functional Strength (30-Second Chair Stand Test)

    Time frame: Baseline, Week 4, and Week 8

    Lower extremity functional strength will be evaluated using the 30-Second Chair Stand Test, which measures the number of full stands completed within 30 seconds.

Secondary outcomes

  1. Health-Related Quality of Life Assessed by the Short Form-12 (SF-12)

    Time frame: Baseline, at the 4th weeks and at the end of 8 weeks

    Health-related quality of life will be evaluated using the Short Form-12 (SF-12) Health Survey, which assesses physical and mental health components.

Study contacts

Contact information is provided by the study sponsor or research team.

Ekin UĞUR CANÖZ, MSc

CONTACT

[email protected]

+905374525191

Mine Gülden G Polat, PhD

CONTACT

[email protected]

+90216 777 57 00 ext. 5710

Sponsors and collaborators

Lead sponsor

Marmara University

Other

Registry information

Official study title

Investigation of the Effectiveness of Neuromuscular Control-Based Exercises Combined With Aerobic and Strength Training Exercises on Balance in Overweight and Obese Individuals

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 28, 2026
Registry last updated
Jan 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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