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Completed

NCT Number: NCT00428779

Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

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Key information

Conditions

Healthy

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Pr André GEYSSANT

Saint-Etienne, 42055, France

About this study

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
  • The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion criteria

  • The subjects will not be selected if:
  • they were injured in the 3 months before the experiment
  • they had a tendon or joint pathology that could impair strength measurements.
  • they participate to an other experiment at the same time

Treatment and study plan

running during 24 hours without sleep

Procedure

patients running during 24 hours without sleep

no sleeping

Other

patients without sleep during 24 hours

Primary outcomes

  1. -Voluntary and electrically evoked forces on the contracted muscles

    Time frame: 24 hours

Secondary outcomes

  1. Electrically evoked forces on the relaxed muscles and associated EMG activity

    Time frame: 24 hours

  2. Blood samples before the exercise

    Time frame: every 4 hours

  3. Muscle biopsy (vastus lateralis)

    Time frame: before and after the exercise

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne

Other

Registry information

Official study title

Neuromuscular and Cognitive Fatigue During a 24h Treadmill Running Exercise.

Important dates

Study start
2007
Primary completion
2007
Study completion
2007
First posted
Jan 30, 2007
Registry last updated
Jun 11, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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