Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease

Primary outcomes

1. Screening for Neurological manifestations among children diagnosed with inflammatory bowel disease in Assiut university children hospital

   Time frame: during the period from January 2026 to January 2027.

   Neurologic symptoms have a great importance in early diagnosis and

   treatment preventing major morbidity and later sequelae, especially if they

   precede GI symptoms

   The prevalence of neurologic manifestations of IBD varies between 0.2% and

   36%. Their pathogenesis of neurologic manifestations in IBD consists of 6

   mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents

   3.infections complicating immune suppression 4.side effects of medications or

   iatrogenic as a surgical complication 5.thromboembolism 6.immunological

   factors

   UC patients are similar to or higher than CD patients in the probability of

   neurologic symptoms. Neurologic manifestations and complications include:

   headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures,

   neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular

   dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating

   disorders and migraine

2. screen for neurologic and psychiatric disorders in children and adolescents with IBD.

   Time frame: 1 year