Skip to main content
OpenTrials
Completed

NCT Number: NCT07643701

Neurodynamic Mobilization for Cervical Radiculopathy

Cervical radiculopathy is a condition caused by compression or irritation of cervical nerve roots, leading to neck pain, arm pain, sensory disturbances, and functional limitations. This randomized controlled trial evaluated whether adding neurodynamic mobilization to conventional physiotherapy improves pain intensity and functional disability in individuals with cervical radiculopathy. Participants received either conventional physiotherapy alone or conventional physiotherapy combined with neurodynamic mobilization over a 5-week treatment period.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Cervical Radiculopathy Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Radiculopathy

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Lebanese German University

Jounieh, Beirut, 0000, Lebanon

About this study

Cervical radiculopathy is a condition where a nerve in the neck becomes irritated or compressed. This can cause neck pain, pain that spreads into the arm, numbness, tingling, and difficulty performing daily activities. It can significantly affect a person's quality of life.

This study investigated whether adding a specific physiotherapy technique called neurodynamic mobilization to standard physiotherapy could improve recovery in patients with cervical radiculopathy.

A total of 50 participants took part in the study. They were randomly divided into two groups. One group received standard physiotherapy treatment only, while the other group received standard physiotherapy combined with neurodynamic mobilization techniques.

Both treatment programs were carried out over five weeks, with a total of 10 treatment sessions.

Participants were evaluated before and after treatment to measure pain levels and how much their neck condition affected daily activities. Pain was measured using a simple rating scale, and disability was measured using a questionnaire.

The results showed that both groups improved over time. However, the group that received the additional neurodynamic mobilization experienced greater reductions in pain and better improvement in daily function compared to the group that received standard physiotherapy alone.

The study suggests that adding neurodynamic mobilization may enhance the effectiveness of physiotherapy for people with cervical radiculopathy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18-65 years.
  • Diagnosis of cervical radiculopathy.
  • pain radiating to the upper limb.
  • Presence of at least one neurological sign, including: Sensory deficit, or Muscle weakness, or Diminished reflexes.

Exclusion criteria

  • Previous cervical spine surgery.
  • Cervical myelopathy.
  • Cervical fractures.
  • Tumors affecting the cervical spine.
  • Inflammatory disorders.
  • Any contraindication to physiotherapy interventions.

Treatment and study plan

Neurodynamic mobilization

Other

Neurodynamic mobilization consisted of specific neural tissue mobilization techniques targeting the affected cervical nerve roots. The techniques were applied in addition to conventional physiotherapy and aimed to restore normal neural mobility and reduce mechanosensitivity. Treatment was delivered over 5 weeks (10 sessions). Each session included standardized neurodynamic sliding techniques performed within pain-free or low-pain ranges, combined with conventional physiotherapy interventions including therapeutic exercises, manual therapy, and physical modalities. The intervention was individually tailored based on patient symptoms and clinical presentation.

Conventional Physiotherapy

Other

Conventional physiotherapy consisted of a standardized rehabilitation program including therapeutic exercises, manual therapy techniques, and physical modalities. Therapeutic exercises focused on cervical range of motion, strengthening, and postural correction. Manual therapy included soft tissue techniques and joint mobilization of the cervical spine. Physical modalities were applied to reduce pain and improve function. The intervention was delivered over 5 weeks, with a total of 10 sessions.

Primary outcomes

  1. Pain Intensity

    Time frame: Baseline and after 5 weeks of intervention.

    Pain intensity will be assessed using the Visual Analogue Scale (VAS), a validated self-reported measure of pain severity. The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.

Secondary outcomes

  1. Functional Disability

    Time frame: Baseline and after 5 weeks of intervention.

    Functional disability will be assessed using the Neck Disability Index (NDI), a validated questionnaire designed to evaluate the impact of neck pain on daily activities. The NDI consists of 10 items, with total scores ranging from 0 to 50. Higher scores indicate greater neck-related disability.

Sponsors and collaborators

Lead sponsor

Lebanese German University

Other

Registry information

Official study title

Effectiveness of Adding Neurodynamic Mobilization to Conventional Physiotherapy in Patients With Cervical Radiculopathy: A Randomized Controlled Trial

Acronym: NDM-CR

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 11, 2026
Registry last updated
Jun 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.