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NCT Number: NCT01074866

Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction

The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive ventilation (NIV)for an episode of acute respiratory failure of various origin.

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Key information

Conditions

Non Invasive Ventilation Patient Ventilator Interaction

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

St Luc University hospital, Brussels, Belgium

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About this study

The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive ventilation (NIV)for an episode of acute respiratory failure of various origin. The subgroup of COPD patients will be analyzed separately. The effects of various setting of Neurally adjusted ventilatory assist on patient-ventilator interaction will also be explored.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients admitted to the ICU and treated with Non invasive ventilation for acute respiratory failure of any origin

Exclusion criteria

  • severe hypoxemia requiring an FIO2>0.6
  • hemodynamic instability
  • known oesophageal problem
  • active upper gastro-intestinal bleeding
  • any other contraindication to the insertion of a naso-gastric tube
  • impaired consciousness or absence of patient cooperation
  • facial or laryngeal lesions contraindicating the use of NIV
  • poor short term prognosis

Treatment and study plan

Neurally Adjusted Ventilatory Assist

Device

Non invasive ventilation under Neurally adjusted Ventilatory Assist

Other names: NAVA

Primary outcomes

  1. Patient-ventilator synchronization parameters

Sponsors and collaborators

Lead sponsor

University Hospital, Geneva

Other

Collaborators

  • Notre Dame de Grace Hospital, Gosselies
  • University Hospital Sart Tilman, Liege
  • University Hospital St Luc, Brussels
  • University of Lausanne Hospitals

Registry information

Official study title

The Effects of Neurally Adjusted Ventilatory Assist (NAVA) on Improving Patient-ventilator Interaction in Patients Undergoing Ventilation for Acute Respiratory Failure

Important dates

Study start
2010
Primary completion
2010
Study completion
2011
First posted
Feb 24, 2010
Registry last updated
Sep 21, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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