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Completed

NCT Number: NCT05314465

Neural Mobilization for Reduction of Spasticity in Stroke

Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and improving upper limb strength. This study aimed to explore and understand the effectiveness of neural mobilization on reduction of spasticity and improving upper limb strength in individuals with stroke. This is mixed method approach of embedded design, multicentric study recruited 7 individuals with stroke as no new themes or codes were emerging (data saturated). Median nerve mobilization was given 20 oscillations per minute for 3 times & repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks. Outcome measures were Modified Ashworth Scale (MAS), Brunnstrom's grading of hand recovery and Hydraulic hand dynamometer(HHD) for grip and pinch strength. Pre and post outcomes data were collected at baseline and 4weeks after intervention and in depth face to face structured interviews was conducted after 4weeks of intervention to explore the effectiveness of median nerve mobilization on reduction of spasticity and the improvement of upper limb strength.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Muscle Hypertonia Muscle Spasticity Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Maharishi Markandeshwar Institute of Physiotherapy & Rehabilitation, Ambāla, Haryana, India

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About this study

Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and improving upper limb strength. This study aimed to explore and understand the effectiveness of neural mobilization on reduction of spasticity and improving upper limb strength in individuals with stroke. This is mixed method approach of embedded design, multicentric study recruited 7 individuals with stroke as no new themes or codes were emerging (data saturated). Median nerve mobilization was given 20 oscillations per minute for 3 times & repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks. Primary outcome measure was Modified Ashworth Scale (MAS) to assess elbow and wrist flexors spasticity and secondary outcome measures were Brunnstrom's stages for hand recovery and Hydraulic hand dynamometer(HHD) to measure grip and pinch strength. Pre and post outcomes data were collected at baseline and 4weeks after intervention and in depth face to face structured interviews was conducted after 4weeks of intervention to explore the effectiveness of median nerve mobilization on reduction of spasticity and the improvement of upper limb strength.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants with subacute and chronic stroke (1month and above) having upper limb spasticity.
  • Participants with haemorrhagic and ischemic stroke.
  • Participants who tolerate the supine position.
  • Participants who are oriented and alert.
  • Both males and females.
  • Participants older than 18 years.

Exclusion criteria

  • Participants with a score greater than 3 on The Modified Ashworth Scale.
  • Participants with affected speech.
  • Participants with upper limb deformity.
  • Participants experiencing dizziness.
  • Any increase in the dosage of anti-spastic medications during the intervention period.
  • General health problems or pathologies that affect the nervous system like uncontrolled diabetes, hypertension and recent surgeries.
  • Recent onset of worsening neurological signs.

Treatment and study plan

Median Nerve Mobilization

Other

Median nerve mobilization was given 20 oscillations per minute for 3 times & repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks.

Primary outcomes

  1. Modified Ashworth Scale (MAS)

    Time frame: Change from baseline and 4 weeks

    For spasticity, Total 4 grades are there. Grade 0 means no increase in muscle tone and grade 4 means affected part rigid in flexion or extension. More grade means more spasticity is there.

Secondary outcomes

  1. Brunnstrom's stages for hand recovery

    Time frame: Change from baseline and 4 weeks

    To check recovery of hand functions. Total 7 grades are there. Increase in grade means increase in hand functions.

  2. Hydraulic hand dynamometer

    Time frame: Change from baseline and 4 weeks

    For grip and pinch strength

Sponsors and collaborators

Lead sponsor

Asir John Samuel

Other

Registry information

Official study title

Effectiveness of Neural Mobilization on Spasticity and Upper Limb Function in Individuals With Stroke

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Apr 6, 2022
Registry last updated
Aug 17, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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