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NCT Number: NCT07323225

Neural Mobilization and Capsular Stretching in Adhesive Capsulitis

Restriction of glenohumeral (GH) mobility in patients with adhesive capsulitis (AC) was known owing to capsular adhesion. There is a little evidence about the involvement of neural restriction in limiting range of motion (ROM) of the GH joint in patients with AC. Objectives: The purpose of this study is to investigate the combined effect of median nerve mobilization and capsular stretching on improving shoulder external rotation, abduction and internal rotation ROM among patients with AC. Methods Thirty patients will be randomly assigned into two equal groups : Group (A) will receive median nerve mobilization and capsular stretching while Group (B) will receive only capsular stretching (anterior, posterior and anteroinferior capsular stretching). Both groups will receive passive and self-assisted exercises. All patients in both groups will be evaluated pre and post treatment for GH external rotation, abduction and internal rotation ROM.

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Key information

Conditions

Adhesive Capsulitis Bursitis Joint Diseases Musculoskeletal Diseases

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Prince Sattam bin Abdulaziz University

Al Kharj, 16242, Saudi Arabia

Location contact

Mohammed, Phd

CONTACT

[email protected]

00966115886387 ext. 00966115886387

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients from both gender (male &female) will be included if they would have second or third stage AC with their age between forty and seventy years
  • experiencing pain, capsular adhesions, and a reduction of greater than fifty percentage in passive ROM of the GH joint (external rotation, abduction, and internal rotation compared to the sound side
  • lasting for a minimum of three months. Patients with positive upper limb tension test-1 will be also included in this study

Exclusion criteria

  • they would have stroke,Parkinson's diseases that interfere with shoulder muscles activity
  • diabetes
  • traumatic shoulder conditions
  • glenohumeral osteoarthritis confirmed by x-ray
  • previous surgery, and manipulation of the affected GH joint under general anesthesia
  • Patients with passive elbow extension ROM

Treatment and study plan

capsular stretching plus neural mobilization

Other

anterior, posterior and inferior capsular stretching and neural mobilization

anterior, inferior and posterior capsular stretching

Other

anterior, inferior and posterior glenohumeral capsular stretching

Traditional exercises

Other

stretching exercises for anterior GH musculture plus auto passive exercises and pendulum exercises

Primary outcomes

  1. pain intensity

    Time frame: 4 Weeks

    pain was assessed by VAS which has two ends. the left end indicates no pain where the right end indicates maximal pain

  2. central sensitization

    Time frame: 4 weeks

    central sensitization will be assessed by the the arabic version of central sensitizatuion questionnaire. To understand CSI scores, the following severity categories have been established: subclinical = 0 to 29; mild = 30 to 39; moderate = 40 to 49; severe = 50 to 59; and extreme = 60 to 100

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammed Hegazy

CONTACT

[email protected]

00966566169893 ext. 00966115886387

Sponsors and collaborators

Lead sponsor

Prince Sattam Bin Abdulaziz University

Other

Registry information

Official study title

Effectiveness of Combined Neural Mobilization Techniques and Capsular Stretching Exercises in Patients With Adhesive Capsulitis.

Acronym: RCT

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 7, 2026
Registry last updated
Jan 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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