University of Michigan
Ann Arbor, Michigan, 48109, United States
Location status: Recruiting
Recruiting
NCT Number: NCT05286151
Network Connectivity and Temporal Processing in Adolescents Who Stutter
The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter. The overall project also aims to investigate how performance on rhythm tasks may be related to brain activity (non-clinical trial).
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
9 year–13 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
About this study
Participants in the clinical trial portion of this study will complete rhythm discrimination and finger tapping experiments once a year for 3 years. The study team will compare performance between groups. Participants will also participate in the non-trial portion of the project that includes having magnetic resonance imaging (MRI) each year for 3 years.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Children who stutter:
- English as primary language
- Current or past stuttering diagnosis
Inclusion criteria
Children who do not stutter:
- English as primary language
Exclusion criteria
Children who stutter:
- Diagnosed/under treatment for any neurological or psychiatric conditions
- Head trauma with loss of consciousness
- Major medical illness
- Hearing loss- Language/motor delay (below -2 standard deviations on standardized assessments)
- Face, motor, or reflex abnormalities
Exclusion criteria
Children who do not stutter:
- Personal or family history of stuttering
- Diagnosed/under treatment for any neurological or psychiatric conditions
- Head trauma with loss of consciousness
- Major medical illness
- Hearing loss
- Language/motor delay (below -2 standard deviations on standardized assessments
- Face, motor, or reflex abnormalities
Treatment and study plan
Rhythm discrimination
BehavioralParticipants will complete a rhythm discrimination task once per year for 3 years.
Primary outcomes
-
Rhythm discrimination (d')
Time frame: Year 1
Performance on the rhythm discrimination task will be assessed using a signal detection analysis to distinguish between participants' ability to discriminate same and different rhythms from any general tendency to respond same or different. Hit rates (HRs) and false alarm rates (FARs) will be obtained to calculate d' (a measure of sensitivity; determined by z(HR) - z(FAR)).
-
Rhythm discrimination (d')
Time frame: Year 2
Performance on the rhythm discrimination task will be assessed using a signal detection analysis to distinguish between participants' ability to discriminate same and different rhythms from any general tendency to respond same or different. Hit rates (HRs) and false alarm rates (FARs) will be obtained to calculate d' (a measure of sensitivity; determined by z(HR) - z(FAR)).
-
Rhythm discrimination (d')
Time frame: Year 3
Performance on the rhythm discrimination task will be assessed using a signal detection analysis to distinguish between participants' ability to discriminate same and different rhythms from any general tendency to respond same or different. Hit rates (HRs) and false alarm rates (FARs) will be obtained to calculate d' (a measure of sensitivity; determined by z(HR) - z(FAR)).
Study contacts
Contact information is provided by the study sponsor or research team.
Emily Garnett, PhD
CONTACT
Soo-Eun Chang, PhD
CONTACT
Sponsors and collaborators
Lead sponsor
University of Michigan
Other
Collaborators
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Registry information
Official study title
Subcortical Network Connectivity and Temporal Processing in Children With Persistent and Recovered Stuttering
Important dates
- Study start
- 2022
- Primary completion
- 2027
- Study completion
- 2027
- First posted
- Mar 18, 2022
- Registry last updated
- Oct 23, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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