Nervous System Infections Among Patients With Febrile Seizure

Few studies dealing with the risk of infectious of nervous system and the utility of lumbar puncture and of emergent neuroimaging among patients with simple febrile seizure between 3 and 11 months age and with complex seizure has been reported. None of these studies was multicentric. Recommendations about management of these children are heterogeneous.

The investigators aim to study by an observational retrospective multicentric study the rate of infectious of central nervous system among patients with a complex febrile seizure and among patients between 3 and 11 months age with simple febrile seizure.

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Key information

Conditions

Seizure Brain Diseases Central Nervous System Diseases Encephalitis Febrile Seizure Meningitis Nervous System Diseases Neuroinflammatory Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Seizures Seizures, Febrile Signs and Symptoms

Age range

3 month–5 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hopital Jean Verdier, Bondy, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

febrile (>38°)
Seizure

Exclusion criteria

previous non febrile seizure
known trauma
immunodeficiancy status
Underlying illness

Treatment and study plan

Primary outcomes

Bacterial meningitis

Time frame: 7 days after emergency visit

Results of lumbar puncture or meningitis history in charts
Herpes simplex virus meningitis/encephalitis

Time frame: 7 days after emergency visit

Results of lumbar puncture or meningitis history in charts

Secondary outcomes

emergent intracranial processus

Time frame: 7 days after emergency visit

Sponsors and collaborators

Lead sponsor

Hôpital Armand Trousseau

Other

Collaborators

Centre Hospitalier Intercommunal Creteil
Centre hospitalier Lagny Marne la vallée
Centre hospitalier intercommunal de Poissy
Hopital Universitaire Robert-Debre
Hôpital Jean Verdier
Versailles Hospital

Registry information

Official study title

Nervous System Infections Among Patients With Febrile Seizure : Retrospective Cohort Review of Consecutive Patients Admitted in 7 Pediatric Emergency Departments in Ile-de-France Between 2007 and 2011

Important dates

Study start: 2013
Primary completion: 2014
Study completion: 2014
First posted: Sep 27, 2012
Registry last updated: May 20, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed