Nerve Morphology in Diabetic Patients

The underlying basis of carpal tunnel syndrome and the basis of its increased incidence in diabetes are unknown. The aim of this study was to quantified pathology in an uncompressed nerve (posterior interosseous nerve in the forearm between diabetic and non-diabetic patients with CTS.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Peripheral Neuropathy Carpal Tunnel Syndrome Cumulative Trauma Disorders Diabetes Complications Diabetes Mellitus Endocrine System Diseases Entrapment Neuropathies Median Neuropathy Mononeuropathies Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Sprains and Strains Wounds and Injuries

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Dept. of Hand Surgery, Malmo University Hospital

Malmö, SE-205 02, Sweden

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of carpal tunnel syndrome based in clinical history and symptoms
Confirmed by nerve conduction studies

Exclusion criteria

Other focal nerve entrapments
Cervical radiculopathy
Inflammatory joint disease
Renal failure
Thyroid disorders
Previous wrist fracture
Long-term exposure to vibrating tools
Age under 18

Treatment and study plan

Primary outcomes

Nerve morphology (Fascicular area, myelinated nerve fiber density, endoneurial capillary density and subperineurial space

Sponsors and collaborators

Lead sponsor

Skane University Hospital

Other

Registry information

Official study title

Posterior Interosseous Nerve Pathology May Provide Novel Insights Into Both Predisposition and Potential Vascular Basis for the Development of Carpal Tunnel Syndrome in Diabetic Patients.

Important dates

Study start: 2003
Study completion: 2008
First posted: Mar 5, 2009
Registry last updated: Mar 5, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed