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Completed

NCT Number: NCT04245891

Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section

This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia. The main objective is to compare the initial Apgar score. The records of patients who received norepinephrine are compared to those without norepinephrine. To limit the biases of this type of study, the investigators will apply a propensity score that will include as a variable: age, ASA score, comorbidity, urgency. The patients analysed correspond to the period 2016-2017.

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Key information

Conditions

Caesarean Section;Stillbirth

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

CHU de Nîmes

Nîmes, Gard, 30029, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age > 18
  • Spinal Anesthesia for Cesarean Section

Exclusion criteria

  • sub epidural cesarean section
  • contraindication to spinal anesthesia (allergy, severe heart disease, coagulopathy)

Treatment and study plan

Primary outcomes

  1. lactate level

    Time frame: Just after the birth of the newborn baby

    The primary endpoint is the Umbilical Cord Lactate levels

Secondary outcomes

  1. APGAR Score

    Time frame: 1, 5 and 10 minutes after birth

    APGAR Score

  2. Umbilical Cord arterial PH

    Time frame: Just after the birth

    Umbilical Cord arterial PH

  3. Umbilical Cord venous PH

    Time frame: Just after the birth

    Umbilical Cord venous PH

  4. maternal arterial tension during cesarean section

    Time frame: 0, 5,10,15, 20 25, 30,35,40 minutes after spinal anesthesia

    maternal arterial tension during cesarean section

  5. incidences of mother nausea and vomiting

    Time frame: from beginning to cesarean section end

    incidences of mother nausea and vomiting

  6. use of vasopressors

    Time frame: from beginning to cesarean section end

    use of vasopressors

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Acronym: NECS

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jan 29, 2020
Registry last updated
Jun 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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