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OpenTrials
Completed

NCT Number: NCT01312324

Neoadjuvant Chemotherapy for Locally Advanced Thymic Cancer

We try to evaluate whether neoadjuvant docetaxel plus cisplatin can increase the complete resection rate in advanced thymic carcinoma.

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Key information

Conditions

Locally Advanced Stage III or IV Thymic Cancer Hemic and Lymphatic Diseases Lymphatic Diseases Neoplasms Neoplasms by Site Thoracic Neoplasms Thymus Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Samsung Medical Center

Seoul, 135-710, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • histologically confirmed thymic carcinoma
  • surgically inoperable Masaoka stage III or IV
  • ECOG 0-2
  • at least one measurable disease

Exclusion criteria

  • previous myocardiac infarct history within 1 year before the enrollment.

Treatment and study plan

neoadjuvant docetaxel/cisplatin

Drug

3 cycles of docetaxel plus cisplatin docetaxel 75mg/m2 D1 cisplatin 75mg/m2 D1 every 3 weeks

Primary outcomes

  1. Complete resection rate

    Time frame: 4-8 weeks later after completion of neoadjuvant chemotherapy

Secondary outcomes

  1. the number of patients with adverse events

    Time frame: from enrollment to 6 months after completion of chemotherapy

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Registry information

Official study title

A Prospective, Phase II Trial of Induction Chemotherapy With Docetaxel/Cisplatin for Masaoka Stage III/IV Thymic Epithelial Tumors

Important dates

Study start
2007
Primary completion
2015
Study completion
2016
First posted
Mar 10, 2011
Registry last updated
Apr 20, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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