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Completed

NCT Number: NCT01380613

Neighborhoods, Networks, Depression, and HIV Risk

The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce their risk for HIV.

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Key information

Conditions

HIV Behavior Behavioral Symptoms Depression Drug Use Risk Reduction Behavior

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Lighthouse Studies @ Peer Points- JHSPH

Baltimore, Maryland, 21205, United States

About this study

This study included implementation and evaluation of a small group, randomized controlled, phase II intervention to reduce depressive symptoms and HIV risk behaviors among inner city drug users. The intervention included elements of cognitive behavioral therapy (CBT) for depression among impoverished individuals, emphasizing depressive cognitions and behaviors theorized to be associated with depression and with HIV risk behaviors among mildly to moderately depressed drug users. In addition, the study examined active drug users' social and environmental pathways to depression and subsequent HIV risk behaviors. Specifically, we will hypothesized mediating/moderating effects of neighborhood characteristics, social network factors, and individual level factors on depressive symptoms and HIV risk behaviors.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-55 years old
  • HIV Risk Behavior:

3a. Injected drugs more than 3 times in the past week OR

3b. Snorted/sniffed heroin or cocaine or smoked crack in the past 6 months AND had 1 of the following sex risks in the past 6 months: i) 2 or more sex partners ii) Had a sex partner who injected drugs iii)Had a sex partner who smoked crack iv) Had a sex partner who was HIV+

  • Willingness to attend group sessions

Exclusion criteria

  • Enrolled in another HIV behavioral intervention or depression study in past the 3 years
  • Enrolled in another Lighthouse study in past the 5 years
  • Enrolled in the formative research (Phase 1) or pilot (Phase 2) of the current project.

Treatment and study plan

Workshop

Behavioral

10 session intervention

Workshop control

Behavioral

1 session intervention on standard HIV/STD information

Primary outcomes

  1. Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 6 months

    Time frame: 6 months

  2. Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 12 months

    Time frame: 12 months

Secondary outcomes

  1. Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 6 months

    Time frame: 6 months

  2. Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 6 months

    Time frame: 6 months

  3. Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 12 months

    Time frame: 12 months

  4. Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 12 months

    Time frame: 12 months

Sponsors and collaborators

Lead sponsor

Johns Hopkins Bloomberg School of Public Health

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)

Registry information

Official study title

The Impact of Neighborhoods, Networks, and Depression on Drug Users' HIV Risk

Acronym: Workshop

Important dates

Study start
2007
Primary completion
2013
Study completion
2013
First posted
Jun 27, 2011
Registry last updated
Sep 5, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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