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OpenTrials
Completed

NCT Number: NCT00517725

Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure

The investigators test the hypothesis that different beta-blockers had a different influence on chemoreceptor response and lung diffusion capacity.

Both could influence exercise capacity in normoxic as well as hypoxic conditions.

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Key information

Conditions

Chronic Heart Failure Behavior Cardiovascular Diseases Heart Diseases Heart Failure Hypoxia Motor Activity Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Centro Cardiologico Monzino, University of Milan

Milan, 20138, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Chronic heart failure patients in stable clinical condition

Exclusion criteria

  • No comorbidity
  • NYHA class IV

Treatment and study plan

Carvedilol

Drug

Bisoprolol

Drug

nebivolol

Drug

Primary outcomes

  1. exercise capacity

    Time frame: two months

Secondary outcomes

  1. lung diffusion

    Time frame: two months

Sponsors and collaborators

Lead sponsor

Centro Cardiologico Monzino

Other

Registry information

Official study title

Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure: Effects on Exercise Capacity and Hypoxia, Chemoreceptor Response, Pulmonary Function

Acronym: CARNEBI

Important dates

Study start
2007
Study completion
2010
First posted
Aug 17, 2007
Registry last updated
Sep 16, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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