Natural History Study of Azathioprine Adherence

This study began in 1993 as a prospective, natural history study of renal transplant patients' medication compliance measured by using an electronic monitor on the cap of medication vials. Hypothesis: Poor medication compliance predicts adverse outcomes. Enrollment is closed.

Completed

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Key information

Conditions

Kidney Transplant Behavior Health Behavior Medication Adherence Patient Acceptance of Health Care Patient Compliance Treatment Adherence and Compliance

Age range

16 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Minnesota

Minneapolis, Minnesota, 55455, United States

About this study

The study is complete. Patient recruitment is closed and active patient involvement in the study has ended.
Statistical analysis of monitor records and new patient outcome data continues

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Kidney transplant recipient
Discharged from hospital with functioning graft,not on dialysis
Prescribed azathioprine

Exclusion criteria

Unable to give informed consent
Non English speaking
Previous or concurrent organ transplant other than kidney
Taking liquid form of azathioprine
Followed outside of the United states

Treatment and study plan

observation

Other

Primary outcomes

acute transplant rejection

Time frame: 10 years

Secondary outcomes

Allograft loss

Time frame: 10 years

Sponsors and collaborators

Lead sponsor

Thomas E. Nivens, MD

Indiv

Registry information

Official study title

Measurement of Compliance in Renal Transplant Recipients

Important dates

Study start: 1993
Primary completion: 1999
Study completion: 1999
First posted: Sep 2, 2005
Registry last updated: Oct 4, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed