Natural History of Urticaria Pigmentosa in Children

The purpose of this study is to determine how long the skin lesions usually last and what kind of symptoms and signs children with urticaria pigmentosa may develop over the years. This information will allow physicians to better care for patients who have been diagnosed with this disease and to provide their parents with more complete information regarding what to expect for the future of their child. This research is being done because many unanswered questions remain regarding children with urticaria pigmentosa and its course.

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Key information

Conditions

Urticaria Pigmentosa Immune System Diseases Mast Cell Activation Disorders Mastocytosis Mastocytosis, Cutaneous Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Pigmentation Disorders Skin Diseases Skin Neoplasms Skin and Connective Tissue Diseases

Age range

Up to 18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Children's Hospital of Wisconsin

Milwaukee, Wisconsin, 53226, United States

About this study

This study involves children, of age 0-18 years old who are diagnosed with urticaria pigmentosa during their visit at the Pediatric Dermatology Clinic. Parents and child will be interviewed to gain medical and family history, in addition, the doctor will perform a physical exam and take a photograph. Children older than 4 years of age will complete the "Children Dermatology Life Quality Index." Children less than 4 years of age with an active disease will have laboratory tests requiring a sample of blood (1 teaspoon).

Patients will receive $50 for their first office visit as financial reimbursement for participating in the study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 0-18 years old at diagnosis of UP
3 or more mastocytomas (diagnosis can be based on clinical exam; biopsy only necessary if diagnosis is in question)
patients recruited from Children's Hospital of Wisconsin Dermatology Clinic

Exclusion criteria

Less than 3 mastocytomas
Diffuse mastocytosis
TMEP
residence is out of Wisconsin/Illinois area or the United States

Sponsors and collaborators

Lead sponsor

Medical College of Wisconsin

Other

Collaborators

Society for Pediatric Dermatology

Registry information

Acronym: UP

Important dates

Study start: 2006
Primary completion: 2008
Study completion: 2008
First posted: May 1, 2007
Registry last updated: Dec 8, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed