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Completed

NCT Number: NCT02378584

Natural Cycle Versus Endometrial Preparation for Healthy Blastocyst Transfer

This study evaluates the difference in pregnancy rate transferring a healthy blastocyst in natural or artificial cycle.

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

20 year–42 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

European Hospital, Rome, RM, Italy

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About this study

The aim of the study was to verify the implantation capacity and ongoing pregnancy rate of vitrified warmed euploid blastocyst in natural cycle versus endometrial artificial cycle with gonadotropin-releasing hormone (GnRH-agonist) pituitary suppression.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • frozen-thawed healthy blastocyst

Exclusion criteria

  • post thawed not survival healthy blastocyst

Treatment and study plan

Embryo transfer

Other

healthy blastocyst transfer in natural and hormonal cycle

Other names: drug adminstration, clinical controls

Primary outcomes

  1. clinical pregnancy rate confirmed by ultrasound evidence of fetal heart activity

    Time frame: 12 weeks after embryo transfer

Secondary outcomes

  1. live-birth rate confirmed by the number of born

    Time frame: term pregnancy delivery

  2. cost-benefit of two endometrial preparation protocol

    Time frame: 30 weeks beginning from day 21 of the previous cycle day up to the pregnancy test

    Assessment of drug cost and the count of clinical visit, laboratory dosages and venous sampling

  3. The number of patients with the anxiety and depression increase

    Time frame: Six weeks beginning on the day of treatment start, on the day of progesterone administration, on the day of blastocyst transfer and the pregnancy test

    the psychological questionnaire (HADS) administered on four time point

Sponsors and collaborators

Lead sponsor

European Hospital

Other

Registry information

Official study title

The Clinical Results After Frozen-thawed Healthy Blastocyst Transfer in Natural Cycle Versus Cycle With Endometrial Preparation

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Mar 4, 2015
Registry last updated
Jan 28, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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