Native-RISE (Risk Identification for Suicide and Enhanced Care)

The goal of this research is to test a systems-level suicide prevention strategy, Native-RISE (Risk Identification for Suicide and Enhanced care), that combines predictive analytics and brief contact interventions (BCIs) to reduce suicide in health systems serving Native Americans (NAs). This project aims to prove the effectiveness and scalability of Native-RISE within three Indian Health Service (IHS) health care clinics (Whiteriver, Chinle and Shiprock) already implementing suicide prevention programs and serving the White Mountain Apache Tribe (WMAT) and Navajo Nation (NN).

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Key information

Conditions

Suicide Prevention Behavior Behavioral Symptoms Self-Injurious Behavior Suicide

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chinle Navajo Nation Center for Indigenous Health, Chinle, Arizona, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults aged 18-75
Visit at least one of the three participating IHS clinics
Identified as at risk of suicide by either an existing method or the new Native-RISE risk model algorithm

Exclusion criteria

None

Treatment and study plan

System of Care - combination of algorithm and Brief Contact Intervention

Device

Case managers see the Native-RISE algorithm classification and Clinical Providers receive a risk notification. A resource card is provided to the participant.

Active Comparator - Provider notification of risk status

Behavioral

Clinical Providers receive a risk notification and a resource card is provided to the participant.

Primary outcomes

Rate of suicide attempts among individuals flagged at elevated risk

Time frame: 12 months

Rate of suicide attempts among individuals flagged at elevated risk is tracked through International Classification of Diseases (ICD) codes and chief complaints as recorded in the participating health system.

Secondary outcomes

Number of contacts with Case Managers (Reach of Brief Contact Interventions (BCI))

Time frame: 12 months

Reach of BCI is defined as at least three or more contacts with Case Managers within the first year following identification of elevated risk.

Sponsors and collaborators

Lead sponsor

Johns Hopkins Bloomberg School of Public Health

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2028
Study completion: 2028
First posted: Jan 20, 2025
Registry last updated: Feb 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Enrolling by Invitation