National Retrospective Study Of Recanalization Treatments In Pediatric Arterial Ischemic Stroke

Median time from symptom onset to Imaging (minutes)

Median time from symptom onset to beginning of recanalization treatment (minutes)

Median door-to-needle delay (minutes)

Intracranial hemorrhage (yes/no)

clinically symptomatic (yes/no)

Peripheral hemorrhage (yes/no)

age of onset (year, months)

Mechanism of stroke (CASCADE classification)

stroke location (name of artery territory)

time from symptom onset to beginning of recanalization treatment (minutes)

initial imagine ASPECT Alberta Stroke Program Early CT Score. score (units on an scale). The ASPECTS score is a 10-point quantitative topographic CT scan score used in patients with middle cerebral artery (MCA) stroke. I has also been adapted to be used with MR scans.

All scale ranges : Segmental assessment of the MCA vascular territory is made and 1 point is deducted from the initial score of 10 for every region involved (caudate, putamen, internal capsule, nsular cortex, M1(anterior MCA cortex=frontal operculum), M2(MCA cortex lateral to insular ribbon=anterior temporal lobe), M3(posterior MCA cortex=posterior temporal lobe, M4(anterior MCA territory immediately superior to M1), M5(lateral MCA territory immediately superior to M2), M6(posterior MCA territory immediately superior to M3)

For each scale, values better or worse :

In adults, an ASPECTS score less than or equal to 7 predicts a worse functional outcome at 3 months as well as symptomatic hemorrhage

Association with :Modified Rankin Scale - mRS (Units on a scale)The mRS is a 6-point quantitative measure of functional independence.

All scale ranges:

0=No symptoms at all

• No significant disability despite symptoms; able to carry out all usual duties and activities
• Slight disability; unable to carry out all previous activities, but able to look after own affairs without assistance disability; requiring some help, but able to walk without assistance
• Moderate
• Moderately severe disability; unable to walk without assistance and unable to attend to own bodily needs without assistance
• Severe disability; bedridden, incontinent and requiring constant nursing care and attention
• Dead

For each scales range, values better or worse :

In the literature, good outcome is usually considered for patients with mRS [0-2]. Very good outcome is considered for patients with mRS [0-1]. We will use the same thresholds

Association with :

• The Pediatric Stroke Outcome Measure - PSOM (Units on a scale) =scale has been designed and published to quantify functional consequences of stroke in children. The PSOM is a detailed neurological examination, with outcome scored in terms of degree of impairment in each of language, cognition, and sensorimotor. We wil use the PSOM-SNE version (PSOM-Short Neuro Exam version).

All scale ranges (0-0,5-1 or 2):

• Sensorimotor deficit, Language Deficit - Production, Language Deficit - Comprehension, Cognitive or Behavioural Deficit. Total score on 10

For each scale range, values better or worse:

Total impairment scores (out of a maximum of 10) will be considered as previously published, i.e. total score 0 or 0.5 representing good outcome, and poor outcome ≥1.

All subscales ranges (Normal, Anormal, Not Done):

Level of consciousness, Behaviour, mental status, Language, Cranial nerves, Motor testing, Tendon reflexes, Fine motor coordination, Sensory, Gate