National Plaque Registry and Database

The primary goals of OPeRA consortium:

To develop a national coronary CTA registry with the collaboration of all major cardiac CT centers of Hungary (Országos Plaque Regiszter és Adatbázis - NatiOnal Plaque Registry and DAtabase, OPeRA).

• To develop a novel risk assessment tool (OPeRA score) based on image markers and clinical characteristics.
• To identify and validate novel vulnerable coronary plaque image markers and assess their prognostic value.

Secondary goals:

• To develop a standardized and structured, national coronary CTA reporting system.
• To establish a national quality control system that monitors the quantity of iodinated contrast agent and the patients' radiation dose.

Inclusion criteria

• Age > 18 years
• Subject providing written informed consent
• Scheduled to undergo a clinically indicated coronary CTA

Exclusion criteria

• Age <18 years
• Suspicion of acute coronary syndrome (acute myocardial infarction and unstable angina)
• Recent prior myocardial infarction within 30 days prior to coronary CTA or between coronary CTA and ICA
• Pregnancy or unknown pregnancy status in subject of childbearing potential
• Subject requires an emergent procedure
• Evidence of ongoing or active clinical instability, including acute chest pain (sudden onset), cardiogenic shock, unstable blood pressure with systolic blood pressure <90 mmHg, and severe congestive heart failure (NYHA III or IV) or acute pulmonary edema
• Inability to comply with study procedures