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Active, Not Recruiting

NCT Number: NCT02251665

National Cerebral and Cardiovascular Center (NCVC) Stroke Registry

A single-center registry of patients with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack (TIA) who are emergently managed in the stroke care unit in the National Cerebral and Cardiovascular Center (NCVC) to determine change in underlying characteristics, stroke features and severity, process for diagnosis and acute treatment, and long-term outcomes of stroke/TIA patients over the years.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Stroke, Acute Brain Diseases Brain Ischemia Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Ischemic Attack, Transient Ischemic Stroke Nervous System Diseases Stroke Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

National Cerebral and Cardiovascular Center

Suita, Osaka, 564-8565, Japan

About this study

This is a single-center registry of consecutive patients with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack (TIA) who are emergently managed in the stroke care unit in the National Cerebral and Cardiovascular Center, a flagship stroke center in Japan.

Neurological emergencies other than stroke/TIA and subclinical cerebrobvascular inpatients are also enrolled.

Data are collected and analyzed to determine change in underlying characteristics, stroke features and severity, process for diagnosis and acute treatment, and long-term outcomes of stroke/TIA patients over the years.

The National Cerebral and Cardiovascular Center was founded in 1977 in Suita, Osaka, in order to provide the public with the most advanced treatment for cardiovascular and cerebrovascular diseases and to conduct the highest level of basic as well as applied research on the cardiovascular and cerebrovascular systems.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A patient with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack who are emergently managed in the stroke care unit or stroke units in the National Cerebral and Cardiovascular Center (NCVC)
  • Consent to participate in the registration by a patient or relatives obtained using an opt-out approach by the demonstrating contents of the registration on the hospital bulletin board

Exclusion criteria

  • Patients considered by the investigator to be unsuitable for participating in this registry

Treatment and study plan

No intervention

Other

a single-center prospective observational study

Primary outcomes

  1. The modified Rankin Scale (mRS), a measure of disability

    Time frame: 3 monhts

    mRS scores range from 0 (no symptoms at all) to 6 (death)

Secondary outcomes

  1. Number of participants

    Time frame: at entry

    Also assessing underlying patients' characteristics prior to index stroke/TIA

  2. National Institutes of Health Stroke Scale score

    Time frame: at entry

    Also assessing neurological and cognitive states

  3. Volume of culprit infarcts/hematoma

    Time frame: at entry

    ASPECTS on DWI for ischemia or hematoma volume using the ABC/2 method

  4. The modified Rankin Scale (mRS), a measure of disability

    Time frame: around 3 weeks

    mRS scores range from 0 (no symptoms at all) to 6 (death). Participants will be followed at hospital discharge, an expected average of 3 weeks.

  5. The modified Rankin Scale (mRS), a measure of disability

    Time frame: 1 year

    mRS scores range from 0 (no symptoms at all) to 6 (death)

  6. Events of cardiovascular diseases including stroke/TIA

    Time frame: around 3 weeks

    Participants will be followed at hospital discharge, an expected average of 3 weeks.

  7. Events of cardiovascular diseases including stroke/TIA

    Time frame: 3 months

  8. Events of cardiovascular diseases including stroke/TIA

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

National Cerebral and Cardiovascular Center, Japan

Other

Registry information

Important dates

Study start
2016
Primary completion
2027
Study completion
2028
First posted
Sep 29, 2014
Registry last updated
Nov 9, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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