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Completed

NCT Number: NCT00365703

Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?

The purpose of this study is to find out which method (nasogastric vs. orogastric) of feeding tube for premature infants results in earlier only oral feeding.

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Key information

Age range

Up to 4 month

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Neonatal intensive care unit, Hille Yaffe medical center

Hadera, 38100, Israel

About this study

Preterm infants, even as young as 23 weeks gestational age, can be fed enterally at the first week of life. Coordination of sucking and swallowing, and coordination of both and breathing is necessary for efficient and safe oral feeding, and is not well established before the 35th week gestational age. That is why tube feeding is essential for preterm infants younger than that age.

There is no consensus regarding the best way for the feeding tube, i.e. oral vs. nasal, and whether placing the tube should be continuous or intermittently. Nasogastric tube has been associated with vagal responses. Both tubes may cause gastric perforation.

Development and function of oral feeding has been described. It is known that non-nutritive sucking and early introduction of oral feeding accelerate the transition from tube feeding to oral feeding. It is suggested that the preterm infant may experience a maturational lag in vagal function related to ingestive needs, which may contribute to continued feeding difficulties and may be a measurable marker of subtle neurodevelopmental problems. Both oral and nasal feeding tube may interfere with establishment of efficient oral feeding. The purpose of this study is to see whether there is a difference between oral and nasal tube feeding, regarding the institution of oral feeding.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All preterm infants, born during one year, who required tube feeding, and later discharged from neonatal intensive care unit.

Exclusion criteria

  • Infants who died during hospitalization
  • Infants with severe neurologic deficit (e.g. after Sarnat II-III asphyxia, or as a part of a syndrome
  • Infants with gastrostomy
  • Infants who were transferred to another hospital for any reason (e.g. heart surgery)

Treatment and study plan

Feeding tube insertion

Procedure
  • Orogastric feeding tube
  • Nasogastric feeding tube

Primary outcomes

  1. The mean post conceptual age at which the infant is fed orally only.

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Hillel Yaffe Medical Center

Other Gov

Registry information

Important dates

Study start
2006
Study completion
2007
First posted
Aug 17, 2006
Registry last updated
Dec 19, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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