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NCT Number: NCT07622745

Nasal Surgery in Snoring and Obstructive Sleep Apnea

This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction.

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Key information

Conditions

Nasal Surgery Apnea Dyssomnias Nervous System Diseases Obstructive Sleep Apnea Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Sounds Respiratory Tract Diseases Signs and Symptoms Signs and Symptoms, Respiratory Sleep Apnea Syndromes Sleep Apnea, Obstructive Sleep Disorders, Intrinsic Sleep Wake Disorders Snoring

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Al-Azhar University

Cairo, 11651, Egypt

About this study

Snoring is the noisy breathing that occurs throughout sleep, resulting from the vibration of the structures in the oral cavity, including the soft palate, uvula, tonsils, base of the tongue, epiglottis, as well as pharyngeal walls.

Obstructive sleep apnea syndrome (OSAS) is a respiratory sleep disorder distinguished by repeated episodes of partial or total occlusion of the upper airways throughout sleep. This blockage is typically associated with a decrease (hypopnea) or total cessation (apnea) of airflow in the upper airways, and sustained thoracic-diaphragmatic respiratory movements.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age above 18 years.
  • Both sexes.
  • Patients with anatomical nasal obstruction due to septal deviation, hypertrophied inferior turbinate (HIT), or nasal polyps refractory to medical treatment.
  • Presence of snoring and obstructive sleep apnea (OSA).
  • Fitness for surgery.

Exclusion criteria

  • Central or mixed sleep apnea.
  • Previous nasal surgery.
  • Unfitness for surgery.
  • Pathological obesity.
  • History of cardiopulmonary disease or asthma.

Treatment and study plan

Septoplasty with partial inferior turbinectomy

Procedure

Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.

Nasal polypectomy

Procedure

Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.

Partial inferior turbinectomy

Procedure

Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.

Primary outcomes

  1. Apnea-Hypopnea Index

    Time frame: 3 months postoperatively

    The Apnea-Hypopnea Index (AHI) is a critical metric used to diagnose and rank the severity of sleep apnea. It measures the average number of times your breathing completely stops (apneas) or becomes severely shallow (hypopneas) per hour of sleep.

Secondary outcomes

  1. Snoring index

    Time frame: 3 months postoperatively

    The snoring index was defined as the number of snoring episodes divided by the hours of total sleep time

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Role of Nasal Surgery in Snoring and Obstructive Sleep Apnea

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Jun 3, 2026
Registry last updated
Jun 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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