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Active, Not Recruiting

NCT Number: NCT07185763

Nano-Learning for Improving Compliance Among Older Adults With Sarcopenia

Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

58 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Nursing

Alexandria, 21523, Egypt

About this study

Nanolearning is an innovative pedagogical strategy that delivers content in highly focused, ultra-short learning experiences, often lasting less than two minutes, aimed at teaching a single skill or topic . Typically offered digitally through bite-sized video lessons or interactive practice exercises, it capitalizes on learners' preference for short-form content and informal learning methods, making knowledge acquisition more accessible and manageable for busy individuals. A defining feature of nano-learning is its brevity, with lessons intentionally kept under two minutes to align with contemporary learning habits, such as engaging with short-form videos on platforms like YouTube Shorts and TikTok . Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants were eligible if they were 60 years or older,
  • had a diagnosis of sarcopenia based on a cut-off score of ≥3 of the Sarcopenia Geriatric Scale (SARCO-GS) (Rosas-Carrasco, 2023),
  • able to communicate effectively, and provided informed consent.

Exclusion criteria

  • Exclusion criteria encompassed severe cognitive impairment, debilitating chronic conditions, or unstable medical status that could hinder participation.
  • Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), with a cutoff score of 25 or below used to exclude participants (Nasreddine, 2005).

Treatment and study plan

Nano-Learning interventional program

Behavioral

AI-based Nano-learning videos involves designing ultra-short, single-focus lessons (not exceeding 2 minutes). Each session was delivered in form of some videos.

Primary outcomes

  1. A Composite Physical Function (CPF) Scale

    Time frame: 2 month

    is a validated tool designed to assess functional capacity in older adults across a continuum of daily activities. It consists of 12 items organized hierarchically, beginning with two basic activities of daily living (BADL) related to self-care, eating, and hygiene, followed by eight instrumental activities of daily living (IADL) that assess community functioning such as household chores, shopping, and mobility, and concluded with two advanced activities involving more demanding household tasks and strenuous physical exercise.

Secondary outcomes

  1. Mini Nutritional Assessment-Short Form (MNA-SF)

    Time frame: 2 month

    is a validated screening tool and one of the most widely recognized and well-studied tools for nutritional screening. It is designed to quickly identify older adults who are malnourished or at risk of malnutrition. As a shortened version of the full Mini Nutritional Assessment, it is widely used in clinical, community, and research settings due to its simplicity and time efficiency (Vellas et al., 2006).

  2. Geriatric Depression Scale-Short Form (GDS-SF)

    Time frame: 2 month

    is a 15-item self-report tool designed to evaluate depression and overall well-being in older adults. Respondents indicate how they have felt during the past week by choosing either "Yes" (scored as 1) or "No" (scored as 0). Scores are summed to yield a total ranging from 0 to 15, with 0-4 reflecting no depression, 5-8 indicating mild depression, 9-11 suggesting moderate depression, and 12-15 representing severe depression. In 2013, Elhusseini translated the scale into Arabic, confirming its validity and reliability (r = 0.70). The GDS-SF remains one of the most effective and widely used geriatric-specific screening instruments for detecting depression in older adults (Abd El Fatah et al., 2022; Stone et al., 2019).

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Official study title

Feasibility and Outcomes of Nano-Learning for Improving Compliance With Physical and Nutritional Guidelines and Reducing Late-Life Depression Among Older Adults With Sarcopenia in a Rural Province

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 22, 2025
Registry last updated
Sep 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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