Myopic Macular Haemorrhages

1. To identify the underlying causes of macular haemorrhages in patients with high myopia 2. In the eyes found to have macular haemorrhages secondary to choroidal neovascularisation, we hope to identify the risk factors for the development of choroidal neovascularisation in high myopia 3. To study the functional outcome of these eyes as assessed by visual acuity 4. To study the morphological outcome of these eyes by clinical assessment (and fundal photography) and fluorescein angiography

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Myopic Macular Haemorrhages Choroid Diseases Choroidal Neovascularization Eye Diseases Metaplasia Neovascularization, Pathologic Pathologic Processes Pathological Conditions, Signs and Symptoms Uveal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Singapore National Eye Centre

Singapore, 168751

About this study

Primary Aims

To identify the underlying aetiologies of macular haemorrhages in myopic eyes
To study the functional and morphological outcome of these eyes with macular haemorrhages 6 months later Secondary Aims
To study the subgroup of eyes with myopic choroidal neovascularisation (CNV), in particular the risk factors for CNV in myopes
To study the subgroup of eyes with macular haemorrhages in the absence of CNV

Plan of investigation:

Patient with myopia (>-6.00DS) presents with loss of central vision
Examination reveals a macular haemorrhage
Investigations

Refraction
Axial length*
Fundus fluorescein angiography
Indocyanine green angiography*
Determine if a myopic CNV is present or absent
Management of patient: Treatment vs No treatment

Treatment being

Conventional laser
PDT
Review at 6 months

BCVA
Clinical appearance (fundal photo)
FFA
Review at 12 months

BCVA
Clinical appearance

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

High myopia (greater than -6.00DS)
Macular haemorrhage

Exclusion criteria

Macular haemorrhages from other causes eg. diabetic retinopathy, hypertensive retinopathy
Allergy to fluorescein or indocyanine green dyes

Sponsors and collaborators

Lead sponsor

Singapore National Eye Centre

Other Gov

Registry information

Important dates

Study start: 2004
Study completion: 2006
First posted: Jun 27, 2006
Registry last updated: Jun 27, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed