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OpenTrials
Active, Not Recruiting

NCT Number: NCT05893979

Myopia Control Spectacle Lens Cessation Study

To quantify myopic progression (cycloplegic spherical equivalent refraction - cSER) following the cessation of use of specific spectacle lenses.

To quantify axial length progression following cessation of use of specific spectacle lenses.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Myopia Eye Diseases Juvenile Myopia Myopia Progression Refractive Errors

Age range

9 year–16 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Golden Optometric Group, Whittier, California, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Previously a successfully completed participant in the CYPRESS Extension study;
  • Agree to wear the assigned spectacles constantly except for sleeping, swimming, or other activities in which spectacle wear would be dangerous or otherwise not possible (minimum of 10 hours per day);
  • Willingness to participate in the trial for up to 12 months without contact lens wear;
  • The subject's parent(s) or legal guardian(s) must read, understand, and sign the Statement of Informed Consent and receive a fully executed copy of the form.

Exclusion criteria

  • Known allergy to proparacaine, tetracaine, or tropicamide.

Treatment and study plan

Spectacle lenses

Device

Standard Spectacle Lenses

Primary outcomes

  1. Cycloplegic Spherical Equivalent Refraction (cSER)

    Time frame: 12 months

    Change in cSER

Secondary outcomes

  1. Cycloplegic Spherical Equivalent Refraction (cSER)

    Time frame: 6 months

    Change in cSER

  2. Axial Length (AL)

    Time frame: 12 months

    Change in AL

Sponsors and collaborators

Lead sponsor

SightGlass Vision, Inc.

Industry

Registry information

Official study title

Myopia Control Spectacle Lens Use Cessation Study

Acronym: BIRCH

Important dates

Study start
2023
Primary completion
2026
Study completion
2027
First posted
Jun 8, 2023
Registry last updated
May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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