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Completed

NCT Number: NCT00457717

Myopia Control by Combining Auricular Acupoint and Atropine Eyedrops

This study was designed to compare the difference of using atropine eyedrops alone from atropine combined with the stimulation of auricular acupoints therapy in reducing myopia progression.

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Key information

Conditions

Myopia Eye Diseases Refractive Errors

Age range

6 year–15 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

China Medical University

Taichung, Taiwan

About this study

A total of 64 school-aged children with myopia, fulfilling eligibility criteria, were recruited. They were randomly assigned to three arms:

  • 21 treated with the 0.25 % atropine each night (0.25A).
  • 20 treated with the 0.5 % atropine each night (0.5A).
  • 23 treated with 0.25 % atropine each night together with stimulation of auricular acupoints(0.25A+E).

This protocol was proceeded for at least 6 months.The differences in post-treatment effects of these three groups were statistically accessed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all included patients, age from 6 to 15 years, had myopia (spherical equivalent > -0.5 D) after cycloplegic refraction,
  • The astigmatism and anisometropia were less than 2.0 D,
  • IOP was less than 21 mmHg.

Exclusion criteria

  • the presence of related disease such as infection, ulceration, eyelid disease, ocular and auricular disorders,
  • individuals with amblyopia or strabismus,
  • individuals received any other therapies in the period of study,
  • individuals suffering some sort of haemostasis disorder,
  • individuals did not follow the treatment (eyedrops and/or stimulation of auricular acupoints) over seven days

Treatment and study plan

0.25 % atropine

Drug

0.5 % atropine

Drug

0.25 % atropine+auricular acupoints

Procedure

Primary outcomes

  1. the progression of myopia degree, axial length elongation of eye

Sponsors and collaborators

Lead sponsor

China Medical University, China

Other

Registry information

Important dates

Study start
2005
Study completion
2006
First posted
Apr 6, 2007
Registry last updated
Apr 6, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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