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Completed

NCT Number: NCT03579992

Myoelectric Computer Interface to Reduce Muscle Co-activation After Stroke

This study examines whether in-lab training with a myoelectric-computer interface (MyCI) can reduce abnormal muscle co-activation after stroke.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Northwestern University

Chicago, Illinois, 60611, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Stroke survivors at least 6 months after stroke onset
  • Persistent moderate to severe arm impairment
  • Increased arm tone

Exclusion criteria

  • Substantial impairment of vision, memory, language or concentration
  • Botulinum toxin use in the affected arm
  • Concomitant participation in another research study on the arm

Treatment and study plan

60-min isometric MyCI training

Behavioral

EMG-controlled in-lab training with arm restrained for 60 minutes per session

90-min isometric MyCI training

Behavioral

EMG-controlled in-lab training with arm restrained for 90 minutes per session

90-min movement MyCI training

Behavioral

EMG-controlled in-lab training without restraint for 90 minutes per session

Primary outcomes

  1. Fugl-Meyer Assessment - Upper Extremity

    Time frame: 6 weeks

    Scale 0-66, total score

Secondary outcomes

  1. Fugl-Meyer Assessment - Upper Extremity

    Time frame: 10 weeks

    Scale 0-66, total score

  2. Wolf Motor Function Test

    Time frame: 6 and 10 weeks

    Timed test

  3. Motor Activity Log

    Time frame: 6 and 10 weeks

    30-question test, total score

Other outcomes

  1. Modified Ashworth Scale

    Time frame: 6 and 10 weeks

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Important dates

Study start
2014
Primary completion
2017
Study completion
2017
First posted
Jul 9, 2018
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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