Myocellular Signalling in Skeletal Muscle

The study will investigate myocellular signalling in skeletal muscle after insulin-stimulation and exercise in healthy young men

Completed

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Key information

Conditions

Exercise Behavior Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Insulin Sensitivity Metabolic Diseases Motor Activity Nutritional and Metabolic Diseases

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

August Krogh Building

Copenahgen, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy
informed consent
habitual training (2-5 h/week)
VO2max of 40-60 ml/min/kg
lean mass 55-65 kg

Exclusion criteria

smoker
allergy towards insulin
chronic disease

Treatment and study plan

Insulin

Drug

2 h insulin clamp

Exercise

Other

Cycling exercise

Primary outcomes

Change in muscle phospho-proteome signature

Time frame: Before and after 10 minutes of exercise, as well as before and after a 2 hour insulin stimulation

proteomic analysis of mixed muscle homogenate

Sponsors and collaborators

Lead sponsor

University of Copenhagen

Other

Registry information

Official study title

Insulin-dependent and Exercise-induced Myocellular Signalling in Skeletal Muscle

Important dates

Study start: 2017
Primary completion: 2017
Study completion: 2017
First posted: Jun 29, 2017
Registry last updated: Aug 1, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed