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OpenTrials
Completed

NCT Number: NCT07568587

Myocardial Function Recovery Prediction Post Primary PCI Using the Estimate of Myocardial Salvage in Gated SPECT Early After Acute Myocardial Infarction

Our aim was to correlate functional and perfusion abnormalities early post primary percutaneous coronary intervention after acute myocardial infarction in ST elevation myocardial infarction patients to estimate myocardial salvage, and to predict left ventricular ejection fraction (LVEF) recovery and remodeling in gated SPECT at follow-up.

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Key information

Conditions

ST Elevation Acute Myocardial Infarction

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine

Al Fayyum, Egypt

About this study

Myocardial Salvage and Infarction Size assessed by an early gated Single Photon Emission Computed Tomography Myocardial Perfusion Image study can predict Left Ventricle Ejection Fraction evolution after primary Percutaneous Coronary Intervention for Acute Myocardial Infarction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • STEMI patients underwent primary PCI.

Exclusion criteria

  • Patients who were lost to follow-up at 6 months post index-SPECT MPI study.
  • Patients subsequently underwent a coronary revascularization procedure [percutaneous coronary intervention (PCI) or coronary bypass surgery (CABG)] within 60 days post index-SPECT MPI post PCI.
  • Patients had a documented history of prior MI or coronary revascularization
  • Patients with severe valvular disease and/or non-ischemic cardiomyopathy.
  • Patients with renal and/or hepatic critical illness.

Treatment and study plan

Primary outcomes

  1. Myocardial Salvage assessed by an early gated SPECT Myocardial Perfusion Image study can predict LVEF evolution after primary PCI for Acute Myocardial Infarction.

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Fayoum University

Other

Registry information

Important dates

Study start
2021
Primary completion
2026
Study completion
2026
First posted
May 6, 2026
Registry last updated
May 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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