MYocardial DOmmages Related to COVID-19

Myocardial injury, as assessed by elevation of cardiac troponins (Tnc), is frequent among patients with COVID-19. Although rare autopsy cases reported COVID-19 related myocardial inflammation, the origin of Tnc elevation is unknown to date. Several cardiac causes, such as myocarditis, non-ischemic myocardial injury (NIMI), or myocardial infarction (MI) may lead to Tnc kinetic. Our work will test the hypothesis that during SARS-Cov2 infection, the elevation of cardiac biomarkers could be linked to the occurrence of myocarditis.

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Key information

Conditions

Covid19 COVID-19 Cardiomyopathies Cardiovascular Diseases Coronaviridae Infections Coronavirus Infections Heart Diseases Infarction Infections Ischemia Lung Diseases Myocardial Infarction Myocardial Ischemia Myocarditis Necrosis Nidovirales Infections Non Ischemic Myocardial Injury Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Troponin Elevation Vascular Diseases Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chu Dijon Bourgogne

Dijon, 21000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

COVID-19 positive patient hospitalized < 72 h after symptoms onset with troponin assessement.

Exclusion criteria

patients hospitalized > 72h after symptom onset

Treatment and study plan

Biological data

Biological

Biological data

Clinical data

Other

Clinical data

Primary outcomes

characterize the myocardial damage associated with CoV-2 SARS infection

Time frame: Through study completion, an average of 2 years

Myocardtitis diagnosis in patients COVID+ and troponin+

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire Dijon

Other

Registry information

Acronym: DOMY COVID

Important dates

Study start: 2020
Primary completion: 2022
Study completion: 2022
First posted: Aug 4, 2020
Registry last updated: Sep 22, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed