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OpenTrials
Completed

NCT Number: NCT00657436

Myeloid-Related Protein in Evaluation of Acute Chest Pain in the Emergency Departement

The purpose of the study is the evaluation of multiple biomarkers related to acute coronary syndromes, including myeloid-related protein 8/14 (MRP 8/14), along with established clinical markers, for early diagnosis and risk stratification in patients presenting with acute chest pain at the emergency department.

Study hypothesis: MRP 8/14, alone or together with other established or new biomarkers, increases the earliness, sensitivity, and specificity of diagnosing acute coronary syndromes.

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Key information

Conditions

Myocardial Ischemia Acute Coronary Syndrome Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Artery Disease Coronary Disease Coronary Occlusion Coronary Thrombosis Embolism and Thrombosis Heart Diseases Infarction Ischemia Myocardial Infarction Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Thrombosis Vascular Diseases

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Cardiology, University Hospital

Zurich, 8091, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients in the emergency department of the University Hospital Zurich with measurement of troponin during the routine diagnostic evaluation.

Exclusion criteria

  • Refusal or inability to give informed consent.

Treatment and study plan

Primary outcomes

  1. Diagnosis of acute coronary syndrome

    Time frame: Emergency room and/or hospital stay

Secondary outcomes

  1. Incidence of any acute coronary event

    Time frame: 1 year

  2. Morbidity from coronary artery disease

    Time frame: 1 year

  3. Mortality

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Collaborators

  • Swiss National Science Foundation

Registry information

Official study title

Study of Myeloid-related Protein 8/14 and Additional Biomarkers (Multi Marker Approach) for Early Diagnosis and Risk Stratification in Patients Presenting With Acute Chest Pain at the Emergency Department

Acronym: MyRiAD

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Apr 14, 2008
Registry last updated
May 31, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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