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Completed

NCT Number: NCT03713788

Muscle Stretching - the Potential Role of Endogenous Pain Inhibitory Modulation on Stretch Tolerance

This study investigates the influence of a remote, painful stimulus on stretch tolerance. Half of the participants will receive a conditioning painful stimulus following static stretching while the other half will rest quietly.

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Key information

Conditions

Muscle Stretching Exercises Pain Threshold

Age range

18 year–45 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University College of Northern Denmark

Aalborg, 9220, Denmark

About this study

The effect of stretching on joint range of motion is primarily related to changes in the tolerance to stretch, but the mechanisms underlying this change are still largely unknown.

The nervous system has an inbuilt ability to modulate the perceived magnitude of afferent noxious stimuli via supraspinally mediated endogenous pain inhibition or facilitation and by engaging endogenous mechanisms pain tolerance in healthy individuals is known to increase. Thus increasing the tolerance to pain could potentially increase range of motion following stretching.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Eligibility for participation included the absence of any pain or other conditions that might affect the somatosensory system.

Exclusion criteria

  • Substance abuse,
  • History of neurological or mental disabilities
  • Lack of ability to comply with instructions
  • Delayed onset of muscle soreness.

Treatment and study plan

Cold pressor test

Other

Participants placed their non-dominant hand into cold water for 2 minutes

Primary outcomes

  1. Knee extension range of motion

    Time frame: Passive knee extension range of motion was measured at baseline

    Passively induced knee extension range of motion was measured usind the Biodex system 4 pro isokinetic dynomometer

  2. Change in knee extension range of motion between baseline and post stretch.

    Time frame: Changes in passive knee extension range of motion were measured 5 minutes after baseline measures following stretching

    Changes in passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynomometer

  3. Changes in knee extension range of motion between post stretch and post pain.

    Time frame: Changes in passive knee extension range of motion were measured 5 minutes after post stretch measures following intervention.

    Changes in passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynomometer

Secondary outcomes

  1. Surface electromyography measures of muscle activity

    Time frame: Muscle activity during the passive knee extension motion was measured at baseline

    Muscle activity during the passive knee extension motion were measured using SEMG.

  2. Changes in surface electromyography measures of muscle activity between baseline and post stretch measures.

    Time frame: Changes in muscle activity during the passive knee extension motion were measured 5 minutes after baseline measures following stretching.

    Changes in muscle activity during the passive knee extension motion were measured using SEMG.

  3. Changes in surface electromyography measures of muscle activity between post stretch and post pain measures.

    Time frame: Changes in muscle activity during the passive knee extension motion were measured 5 minutes after post stretch measures following intervention.

    Changes in muscle activity during the passive knee extension motion were measured using SEMG.

  4. Passive resistive torque using the Biodes system 4 pro.

    Time frame: Passive resistive torque during the passive knee extension motion was measured at baseline.

    Passive resistive torque during the passive knee extension motion was measured using the Biodex system 4 pro isokinetic dynamometer.

  5. Changes in passive resistive torque measured using the Biodex system 4 pro between baseline and post stretch measures.

    Time frame: Changes in passive resistive torque during the passive knee extension motion was measured 5 minutes after baseline measures following stretching.

    Changes in passive resistive torque during the passive knee extension motion was measured using the Biodex system 4 pro isokinetic dynamometer.

  6. Changes in passive resistive torque measured using the Biodex system 4 pro between post stretch and post pain measures.

    Time frame: Passive resistive torque during the passive knee extension motion was measured 5 minutes after post stretch measures following intervention.

    Changes in Passive resistive torque during the passive knee extension motion was measured using the Biodex system 4 pro isokinetic dynamometer.

Sponsors and collaborators

Lead sponsor

University College of Northern Denmark

Other

Collaborators

  • Aalborg University

Registry information

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Oct 22, 2018
Registry last updated
Oct 22, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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