University of Nottingham
Derby, DE22 3DT, United Kingdom
NCT Number: NCT06205537
This is a prospective, randomized, placebo controlled, double-blinded study to evaluate the efficacy of a combination of nutritional ingredients on muscle health and recovery from a short bout of exhaustive exercise in healthy older adults.
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Notify Me60 year–75 year
All sexes
Interventional
Not applicable
Derby, DE22 3DT, United Kingdom
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Ready to drink supplement.
Ready to drink supplement.
Time frame: Pre-Exercise (Day -1) to Post Exercise Recovery (up to 7 Days)
Change in Peak torque of maximum voluntary contraction (MVC)
Time frame: Pre-Exercise (Day -1) to Post Exercise Recovery (up to 7 Days)
Time to failure during a sub-maximal isometric contraction of the knee extensors
Time frame: Pre-Exercise (Day -1) to Post Exercise Recovery (up to 7 Days)
100 mm visual analog scale from No Pain to Extreme Pain
Time frame: Baseline to Day -1 Pre-Exercise (up to 4 Weeks)
Change in Peak torque of maximum voluntary contraction (MVC)
Time frame: Post Exercise Day 1 to Day 7
Change in Fractional Synthesis Rate
Time frame: Pre-Exercise (Day -1) to Post Exercise Recovery (up to 7 Days)
Change in D3-3methylhistidine (D3-3MH)
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Change in Electromyography
Time frame: Pre-Exercise (Day -1) to Post Exercise Recovery (up to 7 Days)
Changes in blood biomarker of muscle damage
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Changes in blood biomarker of oxidative stress
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Changes in bioelectrical impedance analysis (BIA)
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Change in muscle biopsy markers
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Change in saliva biomarkers
Time frame: Baseline to Pre-Exercise Study Day -1 (up to 4 weeks)
Change in hand grip dynamometer in kg
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Change in Alpha and Beta diversity
Time frame: Baseline to Pre-Exercise Study Day -1 (up to 4 weeks)
Change in 3 domains to assess functional mobility; Scores from 0 to 12 with higher scores indicating better mobility
Time frame: Baseline to Pre-Exercise Study Day -1 (up to 4 weeks)
Participant reported information related to common cold symptoms
Time frame: Baseline to Pre-Exercise Study Day -1 (up to 4 weeks)
Participant completed 36-item health survey resulting in a score from 0 to 100 where higher scores indicate better health status
Time frame: Baseline up to Post Exercise Study Day 7 (up to 5 weeks)
Changes in ultrasound measurements
Abbott Nutrition
Industry
Effects of Nutritional Ingredients on Muscle Health and Recovery Following a Short Bout of Exhaustive Exercise in Older Adults
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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