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OpenTrials
Completed

NCT Number: NCT03868631

Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements

Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis. The purpose of this study is to determine whether matching soy and whey protein supplements for leucine content instead of by total protein content would contribute to differences in strength increases and muscle growth in response to 12 wk of resistance training.

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Key information

Conditions

Skeletal Muscle Growth

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Arizona State University

Phoenix, Arizona, 85004, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • non-smoking
  • body mass index (BMI) 18.5-24.9
  • recreationally active

Exclusion criteria

  • participated in structured weight training during the previous 12 month
  • vegetarian or vegan
  • presence of chronic disease
  • pregnant, postpartum up to six months, lactating, or intention to become pregnant
  • allergy to whey or soy
  • changes in body weight more than 10 pounds in the past three months

Treatment and study plan

Whey Protein Supplement

Dietary Supplement

19 g whey protein isolate (contains 2 g leucine) was consumed daily by one intervention group.

Soy Protein Supplement

Dietary Supplement

26 g soy protein isolate (contains 2 g leucine) was consumed daily by the other intervention group.

Primary outcomes

  1. Lean Body Mass Change

    Time frame: Post-12 week intervention

    assessed using dual energy x-ray absorptiometry (DEXA) scan for changes in lean body mass (kg)

  2. Muscle Tissue Thickness Change

    Time frame: Post-12 week intervention

    assessed using changes in muscle thickness assessed by ultrasound (cm)

  3. Leg Girth Changes

    Time frame: Post-12 week intervention

    assessed using circumference measurements (cm)

Secondary outcomes

  1. Change in Peak Torque When Doing Leg Extensions

    Time frame: Post-12 week intervention

    Assessed using an isokinetic dynamometer set at 60 degrees of motion per second (d/s)

Sponsors and collaborators

Lead sponsor

Point Loma Nazarene University

Other

Registry information

Official study title

Muscle Growth and Development Following a 12-week Resistance Training Program in Men and Women Consuming Soy and Whey Protein Supplements

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Mar 11, 2019
Registry last updated
Feb 27, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.