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OpenTrials
Completed

NCT Number: NCT00975390

Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates

The aim of the present study is to investigate the effect of added protein+leucine or caffeine to 1.2 g/kg/h CHO on the rate of post-exercise muscle glycogen re-synthesis in healthy, recreational athletes.

The investigators hypothesize that both interventions (the addition of caffeine or protein+leucine) will lead to higher glycogen re-synthesis compared to the ingestion of CHO only, and that the co-ingestion of protein and leucine will result in the highest muscle glycogen synthesis rates.

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Key information

Conditions

Exercise Recovery

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Maastricht University

Maastricht, Netherlands

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male cyclists
  • healthy
  • BMI < 25

Exclusion criteria

  • female
  • use of medication
  • non cycling
  • BMI > 25

Treatment and study plan

Carbohydrate

Dietary Supplement

1.2 g/kg/h

Carbohydrate and protein ingestion

Dietary Supplement

1.2 g/kg/h carbohydrate plus 0.4 g/kg/h protein

Carbohydrate and caffeine ingestion

Dietary Supplement

1.2 g/kg/h carbohydrate and 1.67 g/kg/h caffeine

Primary outcomes

  1. Muscle glycogen synthesis rates

    Time frame: 6 hours

Secondary outcomes

  1. Glycogen synthase activity, plasma glucose, insulin, free fatty acids and epinephrine responses

    Time frame: 6 hours

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

The Effect of Caffeine or Protein Co-ingestion With Carbohydrate on Post-exercise Muscle Glycogen Synthesis Rate.

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Sep 11, 2009
Registry last updated
Apr 14, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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