Skip to main content
OpenTrials
Completed

NCT Number: NCT07058480

Muscle Energy Technique and Myofascial Chain Training for Menstrual Pain in Primary Dysmenorrhea (METPD-25)

This prospective clinical trial evaluates the effects of a non-pharmacological intervention combining muscle energy technique (MET) and myofascial chain (MFC)-based pelvic stabilization training in women with primary dysmenorrhea (PD). The study aims to determine whether this combined approach can improve pelvic alignment, reduce menstrual pain, and enhance static balance. Participants are assigned to either an experimental group receiving MET + MFC-based training or a control group receiving conventional physiotherapy. Outcomes include radiographic pelvic parameters, pain intensity, and balance performance.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Shenzhen JianAn Hospital

Shenzhen, Guangdong, 518000, China

About this study

Primary dysmenorrhea (PD) is a common gynecological condition characterized by cyclic lower abdominal pain without an identifiable organic cause. Biomechanical factors such as pelvic misalignment and myofascial imbalance are increasingly recognized as contributing to the persistence and severity of PD.

This prospective non-randomized controlled trial investigates whether a combined intervention of muscle energy technique (MET) and myofascial chain (MFC)-based pelvic stabilization training can improve pelvic structure and reduce clinical symptoms in women with PD. Participants are women aged 18-45 years with moderate-to-severe PD and radiographic evidence of pelvic misalignment. They are assigned to one of two groups:

Experimental group: MET plus MFC-based core stabilization exercises. Control group: Interferential current therapy and deep friction massage. Interventions are administered three times per week for four weeks. The primary outcomes include changes in pelvic sagittal parameters (pelvic tilt, sacral slope, pelvic incidence), pelvic symmetry, menstrual pain (measured by VAS), and static balance (eyes-closed single-leg stance). Assessments are conducted at baseline, 4 weeks, and 12 weeks post-intervention.

The study aims to explore whether biomechanical correction of pelvic alignment contributes to pain modulation and functional improvement in women with PD, providing a basis for non-pharmacological rehabilitation strategies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Females aged 18-45 years
  • Regular menstrual cycles
  • Clinically diagnosed with primary dysmenorrhea
  • Visual Analog Scale (VAS) score ≥ 4 during menstruation for at least six consecutive months
  • Radiographic evidence of pelvic tilt, sacral slope deviation, or frontal pelvic asymmetry

Exclusion criteria

  • Secondary dysmenorrhea or diagnosed gynecological pathologies (e.g., endometriosis, ovarian cysts)
  • Pregnancy or lactation
  • Current use of hormonal contraceptives or hormone therapy
  • Ongoing or recent physical therapy targeting the pelvis
  • History of pelvic or spinal surgery
  • Congenital or structural musculoskeletal disorders affecting the lumbopelvic region

Treatment and study plan

Combined MET and MFC-Based Pelvic Stabilization Training

Behavioral

This intervention consisted of a combination of Muscle Energy Technique (MET) for iliac and sacral dysfunctions (20 minutes per session) and myofascial chain-based pelvic stabilization training (including curl-ups, planks, and anti-rotation exercises; 30 minutes per session), targeting pelvic alignment and neuromuscular control. Sessions were conducted 3 times per week, 50 minutes per session, for 4 consecutive weeks.

Interferential current therapy (ICT)

Device

Interferential current therapy (ICT) was applied to the lumbar (lower back), sacroiliac, and iliac crest regions, 3 sessions per week, 20 minutes per session, for 4 weeks.

Deep Friction Massage (DFM)

Behavioral

Deep friction massage was administered to the lumbar, sacroiliac, and iliac crest regions for 30 minutes per session, 3 sessions per week, for 4 weeks.

Primary outcomes

  1. Change in menstrual pain intensity measured by Visual Analog Scale (VAS)

    Time frame: Baseline (pre-intervention), Week 4 (immediate post-intervention), and Week 12 (telephone follow-up to assess sustainability of treatment effects)

    The primary outcome was the change in pain intensity before and after intervention, assessed using the Visual Analog Scale (VAS,0-10). Participants rated their average menstrual pain during the most painful day of menstruation. A reduction in VAS score indicated improvement in dysmenorrhea symptoms.

Secondary outcomes

  1. Change in Pelvic Tilt (PT) Angle

    Time frame: Baseline and Week 4 (end of intervention)

    Change in PT (degrees) from baseline to Week 4, assessed by standardized lateral pelvic radiograph.

  2. Change in Sacral Slope (SS) Angle

    Time frame: Baseline and Week 4 (end of intervention)

    Change in SS (degrees) from baseline to Week 4, assessed by standardized lateral pelvic radiograph.

  3. Change in Pelvic Incidence (PI) Angle

    Time frame: Baseline and Week 4 (end of intervention)

    Change in PI (degrees) from baseline to Week 4, assessed by standardized lateral pelvic radiograph.

  4. Change in Pelvic Asymmetry Score

    Time frame: Baseline and Week 4 (end of intervention)

    Change in pelvic asymmetry assessed by frontal pelvic X-rays from baseline to Week 4. Pelvic asymmetry is determined by a composite score based on iliac crest height discrepancy, anterior/posterior innominate rotation, adduction/abduction shift, and sacral torsion.

  5. Change in Static Balance

    Time frame: Baseline and Week 4 (end of intervention)

    Change in single-leg stance time (seconds, eyes closed) from baseline to Week 4.

Sponsors and collaborators

Lead sponsor

Shanjiao Luo

Other

Registry information

Official study title

Combined Muscle Energy Technique and Myofascial Chain Stabilization Reduces Menstrual Pain and Improves Pelvic Alignment in Women With Primary Dysmenorrhea: A Prospective Study

Acronym: METPD-25

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 10, 2025
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.