Skip to main content
OpenTrials
Completed

NCT Number: NCT05374031

Multiple Sclerosis Intimacy and Sexuality Questionnaire

Aims: This study aimed to psychometrically evaluate the Turkish version of the Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ-15) in women with MS.

Methods: The study included 130 women with MS. The Turkish linguistic validation process of the original English MSISQ-15 was performed according to standardized guidelines. Reliability analysis was evaluated with test-retest analysis and intra-class correlation (ICC). Internal consistency between the items was analyzed using the Cronbach's alpha coefficient. Item analysis results were used to assess the contribution of the items to the scale. In evaluating the validity of the scale, the relationship between the MSISQ and the Female Sexual Function Index (FSFI), the Multiple Sclerosis Quality of Life Questionnaire-54 (MSQOL-54), and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PSIQ-12) was investigated. Psychometric properties were analyzed using internal consistency, test-rest reliability, construct validity, and floor-ceiling effect.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Genital Diseases Immune System Diseases Nervous System Diseases Questionnaires Sexual Dysfunction Sexual Dysfunction, Physiological Urogenital Diseases

Age range

19 year–64 year

Sex eligibility

Female

Study type

Observational

Primary location

Yozgat Bozok University

Yozgat, 66000, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women over the age of 18 who were literate,
  • who did not have any mental problems preventing cooperation and understanding,
  • who were diagnosed with MS

Exclusion criteria

  • Having pelvic organ prolapse stage 2 or more;
  • having a history of relapse in the past 30 days;
  • experiencing loss of balance or gait disturbance caused by a condition other than MS;
  • being pregnant; having a history of gynecological, urological and/or neurological surgery;
  • having a history of cesarean or vaginal birth in the past six months;
  • being sexually inactive; and, having urinary tract infections

Treatment and study plan

Descriptive study

Other

descriptive study

Primary outcomes

  1. Questionnaire

    Time frame: day 1

    Multiple Sclerosis Intimacy and Sexuality Scale is a 15-item self-report measure that assesses the impact of MS symptoms on sexual activity and satisfaction over the past 6 months.Higher scores indicate greater sexual problems.

  2. Questionnaire

    Time frame: day 1

    Female Sexual Function Index is a 19-item scale that evaluates the sexual functions of female patients. The questionnaire consists of 6 separate subdimensions: desire, arousal, lubrication, orgasm, satisfaction, and pain. Higher scores indicate better sexual function.

  3. Questionnaire

    Time frame: day 1

    Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire is an instrument that evaluates sexual function in women with urinary incontinence and/or pelvic organ prolapse. Increasing scores indicate better sexual function.

  4. Questionnaire

    Time frame: day 1

    Global Pelvic Floor Bother Questionnaire is used to evaluate the presence and severity of the most common clinical problems caused by the pelvic floor dysfunction, namely, stress urinary incontinence, frequent and sudden urination sensation, urge incontinence, voiding difficulty, pelvic organ prolapse, obstructive defecation, fecal incontinence, and dyspareunia. A high score indicates more pelvic floor symptom complaints.

  5. Questionnaire

    Time frame: day 1

    Multiple Sclerosis Quality of Life Questionnaire-54 is used to evaluate the quality of life of patients with MS. Higher scores indicate better quality of life.

Sponsors and collaborators

Lead sponsor

Bozok University

Other

Registry information

Official study title

The Multiple Sclerosis Intimacy and Sexuality Questionnaire-15 (MSISQ-15): Validation of the Turkish Version in Patients With Multiple Sclerosis

Important dates

Study start
2021
Primary completion
2021
Study completion
2022
First posted
May 13, 2022
Registry last updated
May 13, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.