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OpenTrials
Completed

NCT Number: NCT02717026

Multimodal Imaging of Retinal Vessels

Retinal blood flow measurement is of scientific and clinical value. For this purpose retinal vessel morphology (such as diameter, vessel wall thickness, etc) determination is crucial. Different imaging modalities might provide divergent results. Thus, quantification of such differences is valuable.

The present study aims to reveal and quantify differences in vessel morphology between fundus photography, fundus angiography, and optical coherence tomography in health and disease.

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Key information

Conditions

Retinal Blood Vessels Age-Related Macular Degeneration Eye Diseases Macular Degeneration Retinal Degeneration Retinal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Ophthalmology, Medical University of Graz

Graz, Styria, 8036, Austria

About this study

This is considered a pilot study and will pe performed on patients scheduled for routine fluorescein angiography.

During the study day the following procedures will be performed:

  • Medical history and concomitant medication
  • Blood pressure and heart rate
  • Assessment of visual acuity using Snellen vision charts
  • Biomicroscopy
  • Intraocular pressure
  • Funduscopy
  • IOL-Master axial length measurement
  • Fundusphotography
  • Optical coherence tomography
  • Fluorescein Angiography Fundus photography analysis will be performed with an automated software and analysis of both angiography and optical coherence tomography will be performed via the devices inbuilt software.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • written informed consent, clear media

Exclusion criteria

  • any abnormality preventing reliable vessel measurement, pregnancy,

Treatment and study plan

optical coherence tomography

Device

Sections including the retinal vasculature will be taken.

Fluorescein Angiography

Device

Video fluorescein angiography from one eye of each subject will be performed

Fundus Photography

Device

30 and 50 degree fundus images

Primary outcomes

  1. retinal vessel diameter

    Time frame: 5 minutes

Secondary outcomes

  1. retinal vessel reflectivity

    Time frame: 5 minutes

Sponsors and collaborators

Lead sponsor

Medical University of Graz

Other

Registry information

Official study title

Retinal Vessel Morphology in Multimodal Imaging

Acronym: MIR

Important dates

Study start
2015
Primary completion
2017
Study completion
2018
First posted
Mar 23, 2016
Registry last updated
Sep 14, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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